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cysQ cysQ cycC-2 cycC-2 cycC cycC cysNC cysNC cysD cysD PSEEN1896 PSEEN1896 nudE nudE PSEEN0244 PSEEN0244 cysG cysG thyA thyA PSEEN1405 PSEEN1405
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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cysQ3'(2'),5'-bisphosphate nucleotidase; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family. (277 aa)    
Predicted Functional Partners:
cycC-2
Adenosine 5'-phosphosulfate kinase; Catalyzes the synthesis of activated sulfate.
 
 
 0.969
cycC
Adenosine 5'-phosphosulfate kinase; Catalyzes the synthesis of activated sulfate.
 
 
 0.968
cysNC
Sulfate adenylyltransferase, subunit 1/adenylylsulfate kinase; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily.
 
 
 0.965
cysD
ATP-sulfurylase, subunit 2 (ATP:sulfate adenylyltransferase); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
 0.964
PSEEN1896
Putative 5'-adenylylsulfate reductase, CysH; Reduction of activated sulfate into sulfite.
  
 
 0.940
nudE
ADP compounds hydrolase nudE; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
    0.838
PSEEN0244
Putative hydrolase, haloacid dehalogenase family, subfamily IA, variant 3; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme.
     
 0.640
cysG
Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.
  
  
 0.566
thyA
Thymidylate synthase (TS) (TSase); Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
  
    0.458
PSEEN1405
Putative sensory box histidine kinase/response regulator hybrid; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; regulator.
  
  
 0.440
Your Current Organism:
Pseudomonas entomophila
NCBI taxonomy Id: 384676
Other names: P. entomophila L48, Pseudomonas entomophila L48, Pseudomonas entomophila str. L48, Pseudomonas entomophila strain L48
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