node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PSEEN1897 | aroA | PSEEN1897 | PSEEN1490 | Putative para-aminodeoxychorismate synthase subunit I PabB; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | Putative prephenate dehydrogenase, putative/3-phosphoshikimate 1-carboxyvinyltransferase AroA; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.548 |
PSEEN1897 | aroC | PSEEN1897 | PSEEN1529 | Putative para-aminodeoxychorismate synthase subunit I PabB; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.944 |
PSEEN1897 | pheA | PSEEN1897 | PSEEN1489 | Putative para-aminodeoxychorismate synthase subunit I PabB; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | Bifunctional chorismate mutase/prephenate dehydratase PheA; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.904 |
PSEEN1897 | trpA | PSEEN1897 | PSEEN0037 | Putative para-aminodeoxychorismate synthase subunit I PabB; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | Tryptophan synthase alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.941 |
PSEEN1897 | trpB | PSEEN1897 | PSEEN0038 | Putative para-aminodeoxychorismate synthase subunit I PabB; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | Tryptophan synthase beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.948 |
PSEEN1897 | trpC | PSEEN1897 | PSEEN0449 | Putative para-aminodeoxychorismate synthase subunit I PabB; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | Indole-3-glycerol phosphate synthase (IGPS); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the TrpC family. | 0.981 |
PSEEN1897 | trpD | PSEEN1897 | PSEEN0448 | Putative para-aminodeoxychorismate synthase subunit I PabB; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.969 |
PSEEN1897 | trpE | PSEEN1897 | PSEEN0444 | Putative para-aminodeoxychorismate synthase subunit I PabB; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] | 0.836 |
PSEEN1897 | trpF | PSEEN1897 | PSEEN1690 | Putative para-aminodeoxychorismate synthase subunit I PabB; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | N-(5'-phosphoribosyl)anthranilate isomerase (PRAI); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the TrpF family. | 0.937 |
PSEEN1897 | trpG | PSEEN1897 | PSEEN0447 | Putative para-aminodeoxychorismate synthase subunit I PabB; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | Anthranilate synthase component II (Glutamine amido-transferase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.999 |
aroA | PSEEN1897 | PSEEN1490 | PSEEN1897 | Putative prephenate dehydrogenase, putative/3-phosphoshikimate 1-carboxyvinyltransferase AroA; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Putative para-aminodeoxychorismate synthase subunit I PabB; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | 0.548 |
aroA | aroC | PSEEN1490 | PSEEN1529 | Putative prephenate dehydrogenase, putative/3-phosphoshikimate 1-carboxyvinyltransferase AroA; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.997 |
aroA | pheA | PSEEN1490 | PSEEN1489 | Putative prephenate dehydrogenase, putative/3-phosphoshikimate 1-carboxyvinyltransferase AroA; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Bifunctional chorismate mutase/prephenate dehydratase PheA; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.998 |
aroA | trpA | PSEEN1490 | PSEEN0037 | Putative prephenate dehydrogenase, putative/3-phosphoshikimate 1-carboxyvinyltransferase AroA; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Tryptophan synthase alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.863 |
aroA | trpB | PSEEN1490 | PSEEN0038 | Putative prephenate dehydrogenase, putative/3-phosphoshikimate 1-carboxyvinyltransferase AroA; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Tryptophan synthase beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.584 |
aroA | trpC | PSEEN1490 | PSEEN0449 | Putative prephenate dehydrogenase, putative/3-phosphoshikimate 1-carboxyvinyltransferase AroA; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Indole-3-glycerol phosphate synthase (IGPS); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the TrpC family. | 0.665 |
aroA | trpD | PSEEN1490 | PSEEN0448 | Putative prephenate dehydrogenase, putative/3-phosphoshikimate 1-carboxyvinyltransferase AroA; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.629 |
aroA | trpE | PSEEN1490 | PSEEN0444 | Putative prephenate dehydrogenase, putative/3-phosphoshikimate 1-carboxyvinyltransferase AroA; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] | 0.654 |
aroA | trpF | PSEEN1490 | PSEEN1690 | Putative prephenate dehydrogenase, putative/3-phosphoshikimate 1-carboxyvinyltransferase AroA; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | N-(5'-phosphoribosyl)anthranilate isomerase (PRAI); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the TrpF family. | 0.665 |
aroA | trpG | PSEEN1490 | PSEEN0447 | Putative prephenate dehydrogenase, putative/3-phosphoshikimate 1-carboxyvinyltransferase AroA; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Anthranilate synthase component II (Glutamine amido-transferase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.650 |