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PSEEN0459 PSEEN0459 hemF hemF hemH hemH hemN hemN PSEEN2434 PSEEN2434 PSEEN0458 PSEEN0458 PSEEN0457 PSEEN0457 argC argC PSEEN0456 PSEEN0456 hemE hemE cysG cysG
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
PSEEN0459Conserved hypothetical protein; Homologs of previously reported genes of unknown function. (121 aa)    
Predicted Functional Partners:
hemF
Coproporphyrinogen III oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX.
 
  
 0.953
hemH
Ferrochelatase (Protoheme ferro-lyase); Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.
 
  
 0.953
hemN
Coproporphyrinogen III oxidase, O2-independent, SAM and NAD(P)H dependent; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the anaerobic coproporphyrinogen-III oxidase family.
    
 0.923
PSEEN2434
Magnesium chelatase, subunit ChII; Function of strongly homologous gene; enzyme.
     
 0.905
PSEEN0458
Putative dioxygenases related to 2-nitropropane dioxygenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme.
       0.724
PSEEN0457
Putative oxidoreductase, short chain dehydrogenase/reductase family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
       0.560
argC
N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
       0.524
PSEEN0456
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
       0.481
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
 
   
 0.462
cysG
Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme.
  
   
 0.451
Your Current Organism:
Pseudomonas entomophila
NCBI taxonomy Id: 384676
Other names: P. entomophila L48, Pseudomonas entomophila L48, Pseudomonas entomophila str. L48, Pseudomonas entomophila strain L48
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