node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PSEEN0434 | PSEEN1429 | PSEEN0434 | PSEEN1429 | Putative DnaJ-like co-chaperone; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; molecular chaperone. | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | 0.482 |
PSEEN0434 | erpA | PSEEN0434 | PSEEN0461 | Putative DnaJ-like co-chaperone; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; molecular chaperone. | Conserved hypothetical protein; Required for insertion of 4Fe-4S clusters for at least IspG. | 0.562 |
PSEEN0434 | iscS-1 | PSEEN0434 | PSEEN1010 | Putative DnaJ-like co-chaperone; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; molecular chaperone. | Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily. | 0.549 |
PSEEN0434 | iscS-2 | PSEEN0434 | PSEEN3349 | Putative DnaJ-like co-chaperone; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; molecular chaperone. | Cysteine desulfurase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.549 |
PSEEN0434 | iscU | PSEEN0434 | PSEEN1011 | Putative DnaJ-like co-chaperone; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; molecular chaperone. | Iron-sulfur cluster assembly protein IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | 0.915 |
PSEEN0434 | nfuA | PSEEN0434 | PSEEN3379 | Putative DnaJ-like co-chaperone; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; molecular chaperone. | Conserved hypothetical protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | 0.857 |
PSEEN1203 | PSEEN1429 | PSEEN1203 | PSEEN1429 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function; Belongs to the glutaredoxin family. Monothiol subfamily. | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | 0.449 |
PSEEN1203 | erpA | PSEEN1203 | PSEEN0461 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function; Belongs to the glutaredoxin family. Monothiol subfamily. | Conserved hypothetical protein; Required for insertion of 4Fe-4S clusters for at least IspG. | 0.609 |
PSEEN1203 | iscU | PSEEN1203 | PSEEN1011 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function; Belongs to the glutaredoxin family. Monothiol subfamily. | Iron-sulfur cluster assembly protein IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | 0.441 |
PSEEN1203 | nfuA | PSEEN1203 | PSEEN3379 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function; Belongs to the glutaredoxin family. Monothiol subfamily. | Conserved hypothetical protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | 0.771 |
PSEEN1429 | PSEEN0434 | PSEEN1429 | PSEEN0434 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Putative DnaJ-like co-chaperone; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; molecular chaperone. | 0.482 |
PSEEN1429 | PSEEN1203 | PSEEN1429 | PSEEN1203 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Conserved hypothetical protein; Homologs of previously reported genes of unknown function; Belongs to the glutaredoxin family. Monothiol subfamily. | 0.449 |
PSEEN1429 | erpA | PSEEN1429 | PSEEN0461 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Conserved hypothetical protein; Required for insertion of 4Fe-4S clusters for at least IspG. | 0.513 |
PSEEN1429 | hscB | PSEEN1429 | PSEEN1013 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Co-chaperone protein Hsc20, HscB; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family. | 0.431 |
PSEEN1429 | iscS-1 | PSEEN1429 | PSEEN1010 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily. | 0.563 |
PSEEN1429 | iscS-2 | PSEEN1429 | PSEEN3349 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Cysteine desulfurase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.563 |
PSEEN1429 | iscU | PSEEN1429 | PSEEN1011 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Iron-sulfur cluster assembly protein IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | 0.612 |
PSEEN1429 | nfuA | PSEEN1429 | PSEEN3379 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Conserved hypothetical protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | 0.513 |
PSEEN4300 | erpA | PSEEN4300 | PSEEN0461 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Conserved hypothetical protein; Required for insertion of 4Fe-4S clusters for at least IspG. | 0.548 |
PSEEN4300 | nfuA | PSEEN4300 | PSEEN3379 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Conserved hypothetical protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | 0.578 |