node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PSEEN0463 | PSEEN3562 | PSEEN0463 | PSEEN3562 | Putative peptidase, M23/M37 family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | Putative membrane-bound lytic murein transglycosylase D MltD; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | 0.650 |
PSEEN0463 | amiC | PSEEN0463 | PSEEN4946 | Putative peptidase, M23/M37 family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | N-acetylmuramoyl-L-alanine amidase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.680 |
PSEEN0463 | anmK | PSEEN0463 | PSEEN0462 | Putative peptidase, M23/M37 family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | Conserved hypothetical protein; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | 0.894 |
PSEEN0463 | mltG-2 | PSEEN0463 | PSEEN1623 | Putative peptidase, M23/M37 family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | Conserved hypothetical protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. | 0.519 |
PSEEN0463 | tyrS | PSEEN0463 | PSEEN0464 | Putative peptidase, M23/M37 family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily. | 0.642 |
PSEEN3562 | PSEEN0463 | PSEEN3562 | PSEEN0463 | Putative membrane-bound lytic murein transglycosylase D MltD; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | Putative peptidase, M23/M37 family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | 0.650 |
PSEEN3562 | amiC | PSEEN3562 | PSEEN4946 | Putative membrane-bound lytic murein transglycosylase D MltD; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | N-acetylmuramoyl-L-alanine amidase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.630 |
PSEEN3562 | anmK | PSEEN3562 | PSEEN0462 | Putative membrane-bound lytic murein transglycosylase D MltD; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | Conserved hypothetical protein; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | 0.404 |
PSEEN3562 | mltG-2 | PSEEN3562 | PSEEN1623 | Putative membrane-bound lytic murein transglycosylase D MltD; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | Conserved hypothetical protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. | 0.535 |
PSEEN3562 | nagZ | PSEEN3562 | PSEEN3718 | Putative membrane-bound lytic murein transglycosylase D MltD; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | Putative beta-N-acetyl-D-glucosaminidase NagZ; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. | 0.420 |
amiC | PSEEN0463 | PSEEN4946 | PSEEN0463 | N-acetylmuramoyl-L-alanine amidase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Putative peptidase, M23/M37 family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | 0.680 |
amiC | PSEEN3562 | PSEEN4946 | PSEEN3562 | N-acetylmuramoyl-L-alanine amidase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Putative membrane-bound lytic murein transglycosylase D MltD; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | 0.630 |
amiC | ampD | PSEEN4946 | PSEEN0927 | N-acetylmuramoyl-L-alanine amidase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | N-acetyl-anhydromuramyl-L-alanine amidase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.426 |
amiC | anmK | PSEEN4946 | PSEEN0462 | N-acetylmuramoyl-L-alanine amidase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Conserved hypothetical protein; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | 0.431 |
amiC | mltG-2 | PSEEN4946 | PSEEN1623 | N-acetylmuramoyl-L-alanine amidase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Conserved hypothetical protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. | 0.564 |
amiC | nagZ | PSEEN4946 | PSEEN3718 | N-acetylmuramoyl-L-alanine amidase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Putative beta-N-acetyl-D-glucosaminidase NagZ; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. | 0.489 |
ampD | amiC | PSEEN0927 | PSEEN4946 | N-acetyl-anhydromuramyl-L-alanine amidase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | N-acetylmuramoyl-L-alanine amidase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.426 |
ampD | anmK | PSEEN0927 | PSEEN0462 | N-acetyl-anhydromuramyl-L-alanine amidase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Conserved hypothetical protein; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | 0.463 |
ampG | anmK | PSEEN4466 | PSEEN0462 | Muropeptide permease AmpG; Function of strongly homologous gene; transporter. | Conserved hypothetical protein; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. | 0.460 |
ampG | nagZ | PSEEN4466 | PSEEN3718 | Muropeptide permease AmpG; Function of strongly homologous gene; transporter. | Putative beta-N-acetyl-D-glucosaminidase NagZ; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. | 0.565 |