STRINGSTRING
ubiX ubiX ubiD ubiD ubiA ubiA PSEEN2640 PSEEN2640 ubiF ubiF PSEEN2523 PSEEN2523 mpl mpl PSEEN0638 PSEEN0638 PSEEN0635 PSEEN0635 PSEEN0640 PSEEN0640 aldB aldB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
ubiX3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. (209 aa)    
Predicted Functional Partners:
ubiD
3-octaprenyl-4-hydroxybenzoate decarboxylase; Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis.
 
 
 0.990
ubiA
4-hydroxybenzoate octaprenyltransferase (4-HB polyprenyltransferase); Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
 
  
 0.956
PSEEN2640
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
    
 0.922
ubiF
2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase; Function of strongly homologous gene; enzyme.
    
 0.912
PSEEN2523
Hypothetical protein; No homology to any previously reported sequences; Belongs to the UbiD family.
 
  
 0.898
mpl
UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase; Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl- meso-diaminopimelate by linking it to UDP-N-acetylmuramate. Belongs to the MurCDEF family. Mpl subfamily.
  
  
 0.843
PSEEN0638
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
       0.805
PSEEN0635
Putative sigma-54 dependent transcriptional regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; regulator.
       0.603
PSEEN0640
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
       0.542
aldB
NAD+ dependent aldehyde dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the aldehyde dehydrogenase family.
     
 0.451
Your Current Organism:
Pseudomonas entomophila
NCBI taxonomy Id: 384676
Other names: P. entomophila L48, Pseudomonas entomophila L48, Pseudomonas entomophila str. L48, Pseudomonas entomophila strain L48
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