node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PSEEN0792 | lepB | PSEEN0792 | PSEEN4291 | Putative preprotein translocase SecG Subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Leader peptidase (signal peptidase I), serine protease; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the peptidase S26 family. | 0.545 |
PSEEN0792 | polA | PSEEN0792 | PSEEN0076 | Putative preprotein translocase SecG Subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | DNA polymerase I, 3'--> 5' polymerase, 5'--> 3' and 3'--> 5' exonuclease; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.529 |
PSEEN0792 | secD | PSEEN0792 | PSEEN1002 | Putative preprotein translocase SecG Subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Preprotein translocase membrane subunit SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.796 |
PSEEN0792 | secE | PSEEN0792 | PSEEN0476 | Putative preprotein translocase SecG Subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Protein translocase subunit SecE; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation; Belongs to the SecE/SEC61-gamma family. | 0.994 |
PSEEN0792 | secF | PSEEN0792 | PSEEN1003 | Putative preprotein translocase SecG Subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Preprotein translocase membrane subunit SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.674 |
PSEEN0792 | secY | PSEEN0792 | PSEEN0510 | Putative preprotein translocase SecG Subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Secretion protein SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.988 |
PSEEN0792 | yajC | PSEEN0792 | PSEEN1001 | Putative preprotein translocase SecG Subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Preprotein translocase, membrane subunit YajC; The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions. | 0.944 |
PSEEN0792 | yidC | PSEEN0792 | PSEEN5556 | Putative preprotein translocase SecG Subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Preprotein translocase subunit YidC; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. | 0.981 |
PSEEN1004 | queA | PSEEN1004 | PSEEN0999 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | S-adenosylmethionine:tRNA ribosyltransferase-isomerase (Queuosine biosynthesis protein); Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | 0.406 |
PSEEN1004 | secD | PSEEN1004 | PSEEN1002 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Preprotein translocase membrane subunit SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.526 |
PSEEN1004 | secF | PSEEN1004 | PSEEN1003 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Preprotein translocase membrane subunit SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.572 |
PSEEN1004 | yajC | PSEEN1004 | PSEEN1001 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Preprotein translocase, membrane subunit YajC; The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions. | 0.446 |
lepB | PSEEN0792 | PSEEN4291 | PSEEN0792 | Leader peptidase (signal peptidase I), serine protease; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the peptidase S26 family. | Putative preprotein translocase SecG Subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | 0.545 |
lepB | secD | PSEEN4291 | PSEEN1002 | Leader peptidase (signal peptidase I), serine protease; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the peptidase S26 family. | Preprotein translocase membrane subunit SecD; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.618 |
lepB | secE | PSEEN4291 | PSEEN0476 | Leader peptidase (signal peptidase I), serine protease; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the peptidase S26 family. | Protein translocase subunit SecE; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation; Belongs to the SecE/SEC61-gamma family. | 0.476 |
lepB | secF | PSEEN4291 | PSEEN1003 | Leader peptidase (signal peptidase I), serine protease; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the peptidase S26 family. | Preprotein translocase membrane subunit SecF; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.673 |
lepB | secY | PSEEN4291 | PSEEN0510 | Leader peptidase (signal peptidase I), serine protease; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the peptidase S26 family. | Secretion protein SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.782 |
lepB | yajC | PSEEN4291 | PSEEN1001 | Leader peptidase (signal peptidase I), serine protease; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the peptidase S26 family. | Preprotein translocase, membrane subunit YajC; The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions. | 0.465 |
lepB | yidC | PSEEN4291 | PSEEN5556 | Leader peptidase (signal peptidase I), serine protease; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the peptidase S26 family. | Preprotein translocase subunit YidC; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. | 0.745 |
polA | PSEEN0792 | PSEEN0076 | PSEEN0792 | DNA polymerase I, 3'--> 5' polymerase, 5'--> 3' and 3'--> 5' exonuclease; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | Putative preprotein translocase SecG Subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | 0.529 |