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csrA-2 csrA-2 csrA-3 csrA-3 csrA csrA fliC fliC hfq hfq ihfA ihfA flgC flgC fliF fliF flgL flgL PSEEN1461 PSEEN1461 PSEEN2424 PSEEN2424
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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csrA-2Carbon storage regulator; A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s). (65 aa)    
Predicted Functional Partners:
csrA-3
Carbon storage regulator; A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
  
  
 
0.906
csrA
Carbon storage regulator; A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s).
  
  
 
0.905
fliC
Type B flagellin; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
 
  
 0.668
hfq
Hfq protein; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family.
   
  
 0.527
ihfA
Integration host factor (IHF), alpha subunit, DNA-binding protein, DNA replication; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family.
  
 
 0.524
flgC
Flagellar cell-proximal portion of basal-body rod FlgC; Function of strongly homologous gene; structural protein; Belongs to the flagella basal body rod proteins family.
 
  
 0.506
fliF
Flagellar basal-body M-ring protein FliF; The M ring may be actively involved in energy transduction. Belongs to the FliF family.
  
  
 0.483
flgL
Flagellar hook-associated protein FlgL; Function of strongly homologous gene; structural protein.
 
  
 0.479
PSEEN1461
Putative sensor protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; regulator.
  
 
 0.467
PSEEN2424
Putative sensor histidine kinase/response regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; regulator.
  
 
 0.467
Your Current Organism:
Pseudomonas entomophila
NCBI taxonomy Id: 384676
Other names: P. entomophila L48, Pseudomonas entomophila L48, Pseudomonas entomophila str. L48, Pseudomonas entomophila strain L48
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