node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PSEEN0535 | mnl | PSEEN0535 | PSEEN3174 | Conserved hypothetical protein, ImcF family; Homologs of previously reported genes of unknown function. | Hypothetical protein; Pore-forming toxin that contributes to the virulence of P.entomophila against Drosophila, playing an important role in host intestinal damage and lethality. Displays cytolytic and hemolytic activity. | 0.400 |
aprA | mnl | PSEEN1550 | PSEEN3174 | Alkaline metalloprotease precursor AprA; Secreted protease which is important for P.entomophila to counteract the local immune response of Drosophila. Can degrade antimicrobial peptides (AMPs), e.g. Diptericin and Cecropin A. Thus, protects P.entomophila from the Drosophila antimicrobial peptides produced by the gut innate immune response, and promotes bacterial persistence in the Drosophila gut and killing of the host. Is responsible for maturation of pro-Monalysin to the active toxin Monalysin, by cleaving its N-terminus ; Belongs to the peptidase M10B family. | Hypothetical protein; Pore-forming toxin that contributes to the virulence of P.entomophila against Drosophila, playing an important role in host intestinal damage and lethality. Displays cytolytic and hemolytic activity. | 0.522 |
mnl | PSEEN0535 | PSEEN3174 | PSEEN0535 | Hypothetical protein; Pore-forming toxin that contributes to the virulence of P.entomophila against Drosophila, playing an important role in host intestinal damage and lethality. Displays cytolytic and hemolytic activity. | Conserved hypothetical protein, ImcF family; Homologs of previously reported genes of unknown function. | 0.400 |
mnl | aprA | PSEEN3174 | PSEEN1550 | Hypothetical protein; Pore-forming toxin that contributes to the virulence of P.entomophila against Drosophila, playing an important role in host intestinal damage and lethality. Displays cytolytic and hemolytic activity. | Alkaline metalloprotease precursor AprA; Secreted protease which is important for P.entomophila to counteract the local immune response of Drosophila. Can degrade antimicrobial peptides (AMPs), e.g. Diptericin and Cecropin A. Thus, protects P.entomophila from the Drosophila antimicrobial peptides produced by the gut innate immune response, and promotes bacterial persistence in the Drosophila gut and killing of the host. Is responsible for maturation of pro-Monalysin to the active toxin Monalysin, by cleaving its N-terminus ; Belongs to the peptidase M10B family. | 0.522 |
mnl | oprB | PSEEN3174 | PSEEN1171 | Hypothetical protein; Pore-forming toxin that contributes to the virulence of P.entomophila against Drosophila, playing an important role in host intestinal damage and lethality. Displays cytolytic and hemolytic activity. | Porin B precursor (Outer membrane protein D1) (Glucose porin); Function of homologous gene experimentally demonstrated in an other organism; transporter. | 0.540 |
mnl | oprB-1 | PSEEN3174 | PSEEN4408 | Hypothetical protein; Pore-forming toxin that contributes to the virulence of P.entomophila against Drosophila, playing an important role in host intestinal damage and lethality. Displays cytolytic and hemolytic activity. | Glucose-selective porin OprB; Function of homologous gene experimentally demonstrated in an other organism; transporter. | 0.540 |
mnl | oprF | PSEEN3174 | PSEEN1750 | Hypothetical protein; Pore-forming toxin that contributes to the virulence of P.entomophila against Drosophila, playing an important role in host intestinal damage and lethality. Displays cytolytic and hemolytic activity. | Outer membrane protein OprF; Function of homologous gene experimentally demonstrated in an other organism; membrane component. | 0.540 |
oprB | mnl | PSEEN1171 | PSEEN3174 | Porin B precursor (Outer membrane protein D1) (Glucose porin); Function of homologous gene experimentally demonstrated in an other organism; transporter. | Hypothetical protein; Pore-forming toxin that contributes to the virulence of P.entomophila against Drosophila, playing an important role in host intestinal damage and lethality. Displays cytolytic and hemolytic activity. | 0.540 |
oprB | oprB-1 | PSEEN1171 | PSEEN4408 | Porin B precursor (Outer membrane protein D1) (Glucose porin); Function of homologous gene experimentally demonstrated in an other organism; transporter. | Glucose-selective porin OprB; Function of homologous gene experimentally demonstrated in an other organism; transporter. | 0.545 |
oprB | oprF | PSEEN1171 | PSEEN1750 | Porin B precursor (Outer membrane protein D1) (Glucose porin); Function of homologous gene experimentally demonstrated in an other organism; transporter. | Outer membrane protein OprF; Function of homologous gene experimentally demonstrated in an other organism; membrane component. | 0.733 |
oprB-1 | mnl | PSEEN4408 | PSEEN3174 | Glucose-selective porin OprB; Function of homologous gene experimentally demonstrated in an other organism; transporter. | Hypothetical protein; Pore-forming toxin that contributes to the virulence of P.entomophila against Drosophila, playing an important role in host intestinal damage and lethality. Displays cytolytic and hemolytic activity. | 0.540 |
oprB-1 | oprB | PSEEN4408 | PSEEN1171 | Glucose-selective porin OprB; Function of homologous gene experimentally demonstrated in an other organism; transporter. | Porin B precursor (Outer membrane protein D1) (Glucose porin); Function of homologous gene experimentally demonstrated in an other organism; transporter. | 0.545 |
oprB-1 | oprF | PSEEN4408 | PSEEN1750 | Glucose-selective porin OprB; Function of homologous gene experimentally demonstrated in an other organism; transporter. | Outer membrane protein OprF; Function of homologous gene experimentally demonstrated in an other organism; membrane component. | 0.632 |
oprF | mnl | PSEEN1750 | PSEEN3174 | Outer membrane protein OprF; Function of homologous gene experimentally demonstrated in an other organism; membrane component. | Hypothetical protein; Pore-forming toxin that contributes to the virulence of P.entomophila against Drosophila, playing an important role in host intestinal damage and lethality. Displays cytolytic and hemolytic activity. | 0.540 |
oprF | oprB | PSEEN1750 | PSEEN1171 | Outer membrane protein OprF; Function of homologous gene experimentally demonstrated in an other organism; membrane component. | Porin B precursor (Outer membrane protein D1) (Glucose porin); Function of homologous gene experimentally demonstrated in an other organism; transporter. | 0.733 |
oprF | oprB-1 | PSEEN1750 | PSEEN4408 | Outer membrane protein OprF; Function of homologous gene experimentally demonstrated in an other organism; membrane component. | Glucose-selective porin OprB; Function of homologous gene experimentally demonstrated in an other organism; transporter. | 0.632 |