STRINGSTRING
mnl mnl oprB oprB oprF oprF oprB-1 oprB-1 aprA aprA PSEEN0535 PSEEN0535
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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mnlHypothetical protein; Pore-forming toxin that contributes to the virulence of P.entomophila against Drosophila, playing an important role in host intestinal damage and lethality. Displays cytolytic and hemolytic activity. (271 aa)    
Predicted Functional Partners:
oprB
Porin B precursor (Outer membrane protein D1) (Glucose porin); Function of homologous gene experimentally demonstrated in an other organism; transporter.
     
  0.540
oprF
Outer membrane protein OprF; Function of homologous gene experimentally demonstrated in an other organism; membrane component.
     
  0.540
oprB-1
Glucose-selective porin OprB; Function of homologous gene experimentally demonstrated in an other organism; transporter.
     
  0.540
aprA
Alkaline metalloprotease precursor AprA; Secreted protease which is important for P.entomophila to counteract the local immune response of Drosophila. Can degrade antimicrobial peptides (AMPs), e.g. Diptericin and Cecropin A. Thus, protects P.entomophila from the Drosophila antimicrobial peptides produced by the gut innate immune response, and promotes bacterial persistence in the Drosophila gut and killing of the host. Is responsible for maturation of pro-Monalysin to the active toxin Monalysin, by cleaving its N-terminus ; Belongs to the peptidase M10B family.
      
 0.522
PSEEN0535
Conserved hypothetical protein, ImcF family; Homologs of previously reported genes of unknown function.
      
 0.400
Your Current Organism:
Pseudomonas entomophila
NCBI taxonomy Id: 384676
Other names: P. entomophila L48, Pseudomonas entomophila L48, Pseudomonas entomophila str. L48, Pseudomonas entomophila strain L48
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