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nhaA nhaA PSEEN3649 PSEEN3649 PSEEN3683 PSEEN3683 PSEEN2159 PSEEN2159 PSEEN1611 PSEEN1611 PSEEN2590 PSEEN2590 kefB kefB arsB arsB birA birA gltB gltB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Score
nhaASodium:proton antiporter NhaA; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family. (400 aa)    
Predicted Functional Partners:
PSEEN3649
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
   
    0.650
PSEEN3683
Hypothetical protein; No homology to any previously reported sequences.
   
    0.650
PSEEN2159
Putative transcriptional activator, LysR family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; regulator; Belongs to the LysR transcriptional regulatory family.
  
  
 0.519
PSEEN1611
Putative peptidase SppA; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme.
 
      0.517
PSEEN2590
Putative glutathione-regulated potassium-proton antiporter; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; transporter; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.
     
 0.514
kefB
Glutathione-regulated potassium-proton antiporter; Function of strongly homologous gene; transporter; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.
     
 0.514
arsB
Arsenite efflux pump; Involved in arsenical resistance. Thought to form the channel of an arsenite pump; Belongs to the ArsB family.
     
 0.411
birA
Putative biotin-[acetylCoA carboxylase] holoenzyme synthetase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
      
 0.410
gltB
Glutamate synthase [NADPH] large chain precursor (GOGAT); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
     
 0.408
Your Current Organism:
Pseudomonas entomophila
NCBI taxonomy Id: 384676
Other names: P. entomophila L48, Pseudomonas entomophila L48, Pseudomonas entomophila str. L48, Pseudomonas entomophila strain L48
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