node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PSEEN2620 | mfd | PSEEN2620 | PSEEN3715 | Putative excinuclease ABC, UvrA-like; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | Transcription-repair coupling protein; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | 0.764 |
PSEEN2620 | recN | PSEEN2620 | PSEEN0776 | Putative excinuclease ABC, UvrA-like; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | 0.438 |
PSEEN2620 | rpoB | PSEEN2620 | PSEEN0482 | Putative excinuclease ABC, UvrA-like; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.462 |
PSEEN2620 | rpoC | PSEEN2620 | PSEEN0483 | Putative excinuclease ABC, UvrA-like; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | RNA polymerase, beta prime subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.434 |
PSEEN2620 | uvrA | PSEEN2620 | PSEEN0519 | Putative excinuclease ABC, UvrA-like; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | DNA excision repair enzyme subunit, with UvrBC; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. | 0.911 |
PSEEN3716 | PSEEN3717 | PSEEN3716 | PSEEN3717 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Helicase, SNF2/RAD54 family; Function of strongly homologous gene; enzyme. | 0.805 |
PSEEN3716 | mfd | PSEEN3716 | PSEEN3715 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Transcription-repair coupling protein; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | 0.795 |
PSEEN3717 | PSEEN3716 | PSEEN3717 | PSEEN3716 | Helicase, SNF2/RAD54 family; Function of strongly homologous gene; enzyme. | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | 0.805 |
PSEEN3717 | mfd | PSEEN3717 | PSEEN3715 | Helicase, SNF2/RAD54 family; Function of strongly homologous gene; enzyme. | Transcription-repair coupling protein; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | 0.801 |
PSEEN3717 | rpoA | PSEEN3717 | PSEEN0514 | Helicase, SNF2/RAD54 family; Function of strongly homologous gene; enzyme. | RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.738 |
PSEEN3717 | rpoB | PSEEN3717 | PSEEN0482 | Helicase, SNF2/RAD54 family; Function of strongly homologous gene; enzyme. | RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.739 |
PSEEN3717 | rpoC | PSEEN3717 | PSEEN0483 | Helicase, SNF2/RAD54 family; Function of strongly homologous gene; enzyme. | RNA polymerase, beta prime subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.604 |
PSEEN3717 | rpoZ | PSEEN3717 | PSEEN5446 | Helicase, SNF2/RAD54 family; Function of strongly homologous gene; enzyme. | DNA-directed RNA polymerase, omega subunit; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.742 |
mfd | PSEEN2620 | PSEEN3715 | PSEEN2620 | Transcription-repair coupling protein; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | Putative excinuclease ABC, UvrA-like; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | 0.764 |
mfd | PSEEN3716 | PSEEN3715 | PSEEN3716 | Transcription-repair coupling protein; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | 0.795 |
mfd | PSEEN3717 | PSEEN3715 | PSEEN3717 | Transcription-repair coupling protein; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | Helicase, SNF2/RAD54 family; Function of strongly homologous gene; enzyme. | 0.801 |
mfd | pth | PSEEN3715 | PSEEN0855 | Transcription-repair coupling protein; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | 0.674 |
mfd | recN | PSEEN3715 | PSEEN0776 | Transcription-repair coupling protein; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. | 0.741 |
mfd | rpoA | PSEEN3715 | PSEEN0514 | Transcription-repair coupling protein; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.793 |
mfd | rpoB | PSEEN3715 | PSEEN0482 | Transcription-repair coupling protein; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.870 |