STRINGSTRING
nagZ nagZ PSEEN0432 PSEEN0432 chiC chiC PSEEN3719 PSEEN3719 PSEEN3720 PSEEN3720 mpl mpl anmK anmK ampG ampG PSEEN4383 PSEEN4383 lexA lexA amiC amiC
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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nagZPutative beta-N-acetyl-D-glucosaminidase NagZ; Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide- linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N- acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides. Belongs to the glycosyl hydrolase 3 family. NagZ subfamily. (336 aa)    
Predicted Functional Partners:
PSEEN0432
Putative phosphotransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme.
 
  
 0.951
chiC
Chitinase ChiC (small isoform); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the glycosyl hydrolase 18 family.
   
 
 0.903
PSEEN3719
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
 
     0.846
PSEEN3720
Putative transcriptional regulator, TetR family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; regulator.
     
 0.696
mpl
UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl- meso-diaminopimelate ligase; Reutilizes the intact tripeptide L-alanyl-gamma-D-glutamyl- meso-diaminopimelate by linking it to UDP-N-acetylmuramate. Belongs to the MurCDEF family. Mpl subfamily.
 
   
 0.597
anmK
Conserved hypothetical protein; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family.
 
   
 0.576
ampG
Muropeptide permease AmpG; Function of strongly homologous gene; transporter.
 
   
 0.565
PSEEN4383
PTS system, N-acetylglucosamine-specific IIBC component; Function of strongly homologous gene; enzyme.
  
  
 0.524
lexA
Transcriptional repressor for SOS response (signal peptidase of LexA family); Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
       0.500
amiC
N-acetylmuramoyl-L-alanine amidase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
     
 0.489
Your Current Organism:
Pseudomonas entomophila
NCBI taxonomy Id: 384676
Other names: P. entomophila L48, Pseudomonas entomophila L48, Pseudomonas entomophila str. L48, Pseudomonas entomophila strain L48
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