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PSEEN3722 PSEEN3722 lexA lexA PSEEN4605 PSEEN4605 ftsZ ftsZ recN recN PSEEN3612 PSEEN3612 PSEEN0336 PSEEN0336 PSEEN4791 PSEEN4791 PSEEN4513 PSEEN4513 PSEEN1593 PSEEN1593 PSEEN4464 PSEEN4464
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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PSEEN3722Putative cell division inhibitor-related protein, SulA-like; Component of the SOS system and an inhibitor of cell division. Accumulation of SulA causes rapid cessation of cell division and the appearance of long, non-septate filaments. In the presence of GTP, binds a polymerization-competent form of FtsZ in a 1:1 ratio, thus inhibiting FtsZ polymerization and therefore preventing it from participating in the assembly of the Z ring. This mechanism prevents the premature segregation of damaged DNA to daughter cells during cell division. (158 aa)    
Predicted Functional Partners:
lexA
Transcriptional repressor for SOS response (signal peptidase of LexA family); Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
  
  
 0.887
PSEEN4605
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
  
    0.813
ftsZ
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.
    
 
 0.811
recN
DNA repair protein RecN; May be involved in recombinational repair of damaged DNA.
   
  
 0.770
PSEEN3612
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
  
     0.757
PSEEN0336
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
  
     0.745
PSEEN4791
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
  
     0.736
PSEEN4513
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
  
     0.732
PSEEN1593
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
  
     0.729
PSEEN4464
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
  
     0.711
Your Current Organism:
Pseudomonas entomophila
NCBI taxonomy Id: 384676
Other names: P. entomophila L48, Pseudomonas entomophila L48, Pseudomonas entomophila str. L48, Pseudomonas entomophila strain L48
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