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fadB fadB fadA fadA PSEEN0664 PSEEN0664 PSEEN3197 PSEEN3197 fadAx fadAx PSEEN2543 PSEEN2543 pcaF-2 pcaF-2 phbA phbA PSEEN1594 PSEEN1594 fadFx fadFx gcdH gcdH
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
fadBFatty oxidation complex alpha subunit [Includes: Enoyl-CoA hydratase; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family. (715 aa)    
Predicted Functional Partners:
fadA
3-ketoacyl-CoA thiolase; Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed.
 0.999
PSEEN0664
Putative acetyl-CoA acetyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme; Belongs to the thiolase-like superfamily. Thiolase family.
 0.995
PSEEN3197
Putative Acetoacetyl-CoA thiolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme; Belongs to the thiolase-like superfamily. Thiolase family.
 0.995
fadAx
acetyl-CoA acetyltransferase with thiolase domain FadAx; Function of strongly homologous gene; enzyme; Belongs to the thiolase-like superfamily. Thiolase family.
 0.995
PSEEN2543
Putative 3-ketoacyl-CoA thiolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme; Belongs to the thiolase-like superfamily. Thiolase family.
  
 0.994
pcaF-2
Beta-ketoadipyl CoA thiolase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the thiolase-like superfamily. Thiolase family.
 
 0.994
phbA
acetyl-CoA acetyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the thiolase-like superfamily. Thiolase family.
 
 0.994
PSEEN1594
Putative acyl-CoA dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme.
 
 0.985
fadFx
acyl-CoA dehydrogenase protein FadFx; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
 0.982
gcdH
glutaryl-CoA dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 0.981
Your Current Organism:
Pseudomonas entomophila
NCBI taxonomy Id: 384676
Other names: P. entomophila L48, Pseudomonas entomophila L48, Pseudomonas entomophila str. L48, Pseudomonas entomophila strain L48
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