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nadA nadA nadB nadB nadC nadC PSEEN2937 PSEEN2937 PSEEN2060 PSEEN2060 gmk gmk ribD ribD purL purL birA birA srpH srpH cysE cysE
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
Predicted Interactions
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textmining
co-expression
protein homology
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nadAQuinolinate synthetase A; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate; Belongs to the quinolinate synthase A family. Type 1 subfamily. (352 aa)    
Predicted Functional Partners:
nadB
L-aspartate oxidase (quinolinate synthetase B); Catalyzes the oxidation of L-aspartate to iminoaspartate.
 
 0.998
nadC
Nicotinate-nucleotide pyrophosphorylase (quinolinate phosphoribosyltransferase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the NadC/ModD family.
 
 
 0.997
PSEEN2937
Putative nicotinamide mononucleotide transporter PnuC; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; transporter.
 
  
 0.840
PSEEN2060
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
  
  
 0.727
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
  
    0.694
ribD
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
  
  
 0.591
purL
Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.
  
  
 0.561
birA
Putative biotin-[acetylCoA carboxylase] holoenzyme synthetase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
     
 0.558
srpH
Serine O-acetyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
    0.544
cysE
Serine O-acetyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
    0.544
Your Current Organism:
Pseudomonas entomophila
NCBI taxonomy Id: 384676
Other names: P. entomophila L48, Pseudomonas entomophila L48, Pseudomonas entomophila str. L48, Pseudomonas entomophila strain L48
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