node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PSEEN0244 | PSEEN0889 | PSEEN0244 | PSEEN0889 | Putative hydrolase, haloacid dehalogenase family, subfamily IA, variant 3; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | Putative hypoxanthine phosphoribosyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | 0.901 |
PSEEN0244 | PSEEN1936 | PSEEN0244 | PSEEN1936 | Putative hydrolase, haloacid dehalogenase family, subfamily IA, variant 3; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | Putative 5'-nucleotidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | 0.900 |
PSEEN0244 | guaA | PSEEN0244 | PSEEN4392 | Putative hydrolase, haloacid dehalogenase family, subfamily IA, variant 3; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | 0.919 |
PSEEN0244 | guaB | PSEEN0244 | PSEEN4393 | Putative hydrolase, haloacid dehalogenase family, subfamily IA, variant 3; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | Inosine-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.916 |
PSEEN0244 | purA | PSEEN0244 | PSEEN4938 | Putative hydrolase, haloacid dehalogenase family, subfamily IA, variant 3; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.908 |
PSEEN0244 | purH | PSEEN0244 | PSEEN4863 | Putative hydrolase, haloacid dehalogenase family, subfamily IA, variant 3; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.906 |
PSEEN0244 | rdgB | PSEEN0244 | PSEEN0312 | Putative hydrolase, haloacid dehalogenase family, subfamily IA, variant 3; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | Non-canonical purine NTP pyrophosphatase RdgB; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.901 |
PSEEN0244 | surE | PSEEN0244 | PSEEN4192 | Putative hydrolase, haloacid dehalogenase family, subfamily IA, variant 3; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | Stationary-phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.913 |
PSEEN0244 | xpt | PSEEN0244 | PSEEN5411 | Putative hydrolase, haloacid dehalogenase family, subfamily IA, variant 3; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. | 0.907 |
PSEEN0889 | PSEEN0244 | PSEEN0889 | PSEEN0244 | Putative hypoxanthine phosphoribosyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | Putative hydrolase, haloacid dehalogenase family, subfamily IA, variant 3; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | 0.901 |
PSEEN0889 | PSEEN1936 | PSEEN0889 | PSEEN1936 | Putative hypoxanthine phosphoribosyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | Putative 5'-nucleotidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | 0.900 |
PSEEN0889 | guaA | PSEEN0889 | PSEEN4392 | Putative hypoxanthine phosphoribosyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP. | 0.955 |
PSEEN0889 | guaB | PSEEN0889 | PSEEN4393 | Putative hypoxanthine phosphoribosyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | Inosine-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.920 |
PSEEN0889 | purA | PSEEN0889 | PSEEN4938 | Putative hypoxanthine phosphoribosyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.948 |
PSEEN0889 | purH | PSEEN0889 | PSEEN4863 | Putative hypoxanthine phosphoribosyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.942 |
PSEEN0889 | rdgB | PSEEN0889 | PSEEN0312 | Putative hypoxanthine phosphoribosyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | Non-canonical purine NTP pyrophosphatase RdgB; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.911 |
PSEEN0889 | surE | PSEEN0889 | PSEEN4192 | Putative hypoxanthine phosphoribosyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | Stationary-phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.901 |
PSEEN0889 | xpt | PSEEN0889 | PSEEN5411 | Putative hypoxanthine phosphoribosyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. | 0.927 |
PSEEN1936 | PSEEN0244 | PSEEN1936 | PSEEN0244 | Putative 5'-nucleotidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | Putative hydrolase, haloacid dehalogenase family, subfamily IA, variant 3; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | 0.900 |
PSEEN1936 | PSEEN0889 | PSEEN1936 | PSEEN0889 | Putative 5'-nucleotidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | Putative hypoxanthine phosphoribosyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | 0.900 |