Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| PSEEN1997 | dnaN | PSEEN1997 | PSEEN0002 | Putative ATP-dependent DNA helicase, RecQ-like; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | DNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of r [...] | 0.931 |
| PSEEN1997 | mutL | PSEEN1997 | PSEEN4945 | Putative ATP-dependent DNA helicase, RecQ-like; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.925 |
| PSEEN1997 | mutS | PSEEN1997 | PSEEN4187 | Putative ATP-dependent DNA helicase, RecQ-like; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | Methyl-directed mismatch repair, recognize exocyclic adducts of guanosine; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. | 0.847 |
| PSEEN1997 | polA | PSEEN1997 | PSEEN0076 | Putative ATP-dependent DNA helicase, RecQ-like; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | DNA polymerase I, 3'--> 5' polymerase, 5'--> 3' and 3'--> 5' exonuclease; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.972 |
| PSEEN1997 | recA | PSEEN1997 | PSEEN4128 | Putative ATP-dependent DNA helicase, RecQ-like; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | DNA strand exchange and recombination protein with protease and nuclease activity; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.; Belongs to the RecA family. | 0.942 |
| PSEEN1997 | uvrD | PSEEN1997 | PSEEN5504 | Putative ATP-dependent DNA helicase, RecQ-like; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | DNA-dependent ATPase I and helicase II; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.503 |
| PSEEN4947 | amiC | PSEEN4947 | PSEEN4946 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | N-acetylmuramoyl-L-alanine amidase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.869 |
| PSEEN4947 | miaA | PSEEN4947 | PSEEN4944 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Delta(2)-isopentenylpyrophosphate tRNA-adenosine transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | 0.871 |
| PSEEN4947 | mutL | PSEEN4947 | PSEEN4945 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.802 |
| PSEEN4947 | nnrD | PSEEN4947 | PSEEN4948 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Conserved hypothetical protein; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S-and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. | 0.887 |
| PSEEN4947 | polA | PSEEN4947 | PSEEN0076 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | DNA polymerase I, 3'--> 5' polymerase, 5'--> 3' and 3'--> 5' exonuclease; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.489 |
| amiC | PSEEN4947 | PSEEN4946 | PSEEN4947 | N-acetylmuramoyl-L-alanine amidase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | 0.869 |
| amiC | miaA | PSEEN4946 | PSEEN4944 | N-acetylmuramoyl-L-alanine amidase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Delta(2)-isopentenylpyrophosphate tRNA-adenosine transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | 0.893 |
| amiC | mutL | PSEEN4946 | PSEEN4945 | N-acetylmuramoyl-L-alanine amidase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.896 |
| amiC | nnrD | PSEEN4946 | PSEEN4948 | N-acetylmuramoyl-L-alanine amidase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Conserved hypothetical protein; Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S-and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. | 0.855 |
| dnaN | PSEEN1997 | PSEEN0002 | PSEEN1997 | DNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of r [...] | Putative ATP-dependent DNA helicase, RecQ-like; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | 0.931 |
| dnaN | mutL | PSEEN0002 | PSEEN4945 | DNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of r [...] | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.913 |
| dnaN | mutS | PSEEN0002 | PSEEN4187 | DNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of r [...] | Methyl-directed mismatch repair, recognize exocyclic adducts of guanosine; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. | 0.961 |
| dnaN | polA | PSEEN0002 | PSEEN0076 | DNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of r [...] | DNA polymerase I, 3'--> 5' polymerase, 5'--> 3' and 3'--> 5' exonuclease; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.990 |
| dnaN | recA | PSEEN0002 | PSEEN4128 | DNA polymerase III, beta chain; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of r [...] | DNA strand exchange and recombination protein with protease and nuclease activity; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.; Belongs to the RecA family. | 0.831 |
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