STRINGSTRING
rfaE rfaE gmhA gmhA PSEEN0015 PSEEN0015 rfaC rfaC rfaF rfaF PSEEN4988 PSEEN4988 PSEEN1098 PSEEN1098 msbA msbA lpxK lpxK lpxB lpxB kdsA kdsA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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rfaELipopolysaccharide core biosynthesis protein RfaE; Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7- phosphate at the C-1 position to selectively form D-glycero-beta-D- manno-heptose-1,7-bisphosphate; In the C-terminal section; belongs to the cytidylyltransferase family. (473 aa)    
Predicted Functional Partners:
gmhA
Phosphoheptose isomerase with phosphosugar-binding domain; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate.
  
 0.997
PSEEN0015
Putative histidinol-phosphatase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme.
 
  
 0.986
rfaC
ADP-heptose; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
  
 0.868
rfaF
ADP-heptose; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
  
 0.867
PSEEN4988
Putative lipopolysaccharide core biosynthesis protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme.
     
 0.662
PSEEN1098
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
 
   
 0.652
msbA
Lipid A export ATP-binding/permease protein msbA; Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation.
 
   
 0.615
lpxK
Tetraacyldisaccharide 4'-kinase (Lipid A 4'-kinase); Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
 
   
 0.604
lpxB
Lipid A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
 
   
 0.601
kdsA
2-dehydro-3-deoxyphosphooctonate aldolase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the KdsA family.
 
   
 0.589
Your Current Organism:
Pseudomonas entomophila
NCBI taxonomy Id: 384676
Other names: P. entomophila L48, Pseudomonas entomophila L48, Pseudomonas entomophila str. L48, Pseudomonas entomophila strain L48
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