STRINGSTRING
putA putA putP putP PSEEN1405 PSEEN1405 crbA crbA PSEEN3934 PSEEN3934 proC proC gdhA gdhA proA proA proB proB arcB arcB aspQ aspQ
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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putAProline dehydrogenase/delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. (1317 aa)    
Predicted Functional Partners:
putP
Major sodium:proline symporter (SSS family); Catalyzes the sodium-dependent uptake of extracellular L- proline; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
  
  
 0.982
PSEEN1405
Putative sensory box histidine kinase/response regulator hybrid; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; regulator.
  
  
 0.968
crbA
Sensory box histidine kinase CrbA; Function of homologous gene experimentally demonstrated in an other organism; regulator.
  
  
 0.965
PSEEN3934
Putative sodium-solute symporter; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; transporter; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
  
  
 0.963
proC
Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.
   
 0.961
gdhA
Glutamate dehydrogenase, NADP-specific; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
 
 0.956
proA
Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family.
    
 0.955
proB
Gamma-glutamyl kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
    
 0.947
arcB
Ornithine cyclodeaminase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 
 0.944
aspQ
Glutaminase-asparaginase; Function of strongly homologous gene; enzyme; Belongs to the asparaginase 1 family.
   
 
 0.943
Your Current Organism:
Pseudomonas entomophila
NCBI taxonomy Id: 384676
Other names: P. entomophila L48, Pseudomonas entomophila L48, Pseudomonas entomophila str. L48, Pseudomonas entomophila strain L48
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