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tktA tktA tal tal pgi pgi rpe rpe fda fda fbp fbp prs prs tpiA tpiA rpiA rpiA pgm pgm epd epd
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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Score
tktATransketolase 1 thiamin-binding, isozyme; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (665 aa)    
Predicted Functional Partners:
tal
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
 
 0.995
pgi
Glucose-6-phosphate isomerase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the GPI family.
  
 0.987
rpe
D-ribulose-5-phosphate 3-epimerase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the ribulose-phosphate 3-epimerase family.
 0.976
fda
Fructose-1,6-bisphosphate aldolase, class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.
  
 
 0.972
fbp
Fructose-1,6-bisphosphatase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 
 0.965
prs
Ribose-phosphate pyrophosphokinase (Phosphoribosyl pyrophosphate synthetase); Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
  
 
 0.964
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
  
 0.956
rpiA
Ribose 5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate.
 
 
 0.956
pgm
Phosphoglucomutase, alpha-D-glucose phosphate-specific; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 
 0.949
epd
Glyceraldehyde 3-phosphate dehydrogenase; Catalyzes the NAD-dependent conversion of D-erythrose 4- phosphate to 4-phosphoerythronate.
  
 0.949
Your Current Organism:
Pseudomonas entomophila
NCBI taxonomy Id: 384676
Other names: P. entomophila L48, Pseudomonas entomophila L48, Pseudomonas entomophila str. L48, Pseudomonas entomophila strain L48
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