STRINGSTRING
msrA msrA msrB msrB polA polA PSEEN1817 PSEEN1817 PSEEN5149 PSEEN5149 PSEEN1355 PSEEN1355 PSEEN2406 PSEEN2406 dsbE dsbE PSEEN5255 PSEEN5255 metH metH grxC grxC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
msrAPeptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. (222 aa)    
Predicted Functional Partners:
msrB
Peptide methionine sulfoxide reductase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the MsrB Met sulfoxide reductase family.
 
 0.994
polA
DNA polymerase I, 3'--> 5' polymerase, 5'--> 3' and 3'--> 5' exonuclease; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
  
 0.859
PSEEN1817
Putative thiol:disulfide interchange protein dsbE; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme.
   
 0.821
PSEEN5149
Putative glutathione S-transferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme.
     
 0.791
PSEEN1355
Putative thioredoxin; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; carrier.
   
 0.699
PSEEN2406
Putative thioredoxin; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme.
   
 0.699
dsbE
Thiol:disulfide interchange protein DsbE; Function of strongly homologous gene; enzyme.
   
 0.699
PSEEN5255
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
   
 0.696
metH
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
 
  
 0.630
grxC
Glutaredoxin; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.
 
 
 0.627
Your Current Organism:
Pseudomonas entomophila
NCBI taxonomy Id: 384676
Other names: P. entomophila L48, Pseudomonas entomophila L48, Pseudomonas entomophila str. L48, Pseudomonas entomophila strain L48
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