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pyrE pyrE pyrF pyrF pyrD pyrD pyrB pyrB carA carA prs prs pyrR pyrR PSEEN1146 PSEEN1146 benC benC PSEEN5329 PSEEN5329 PSEEN3251 PSEEN3251
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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pyrEOrotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (213 aa)    
Predicted Functional Partners:
pyrF
Orotidine-5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.
  
 
 0.990
pyrD
Dihydroorotate oxydase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
  
 0.985
pyrB
Aspartate carbamoyltransferase, catalytic subunit; Function of strongly homologous gene; enzyme; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
  
  
 0.913
carA
Carbamoyl-phosphate synthase, small chain; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the CarA family.
 
  
 0.909
prs
Ribose-phosphate pyrophosphokinase (Phosphoribosyl pyrophosphate synthetase); Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
  
 
 0.880
pyrR
Putative transcriptional regulator PyrR; Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.
  
  
 0.858
PSEEN1146
Putative ferredoxin reductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme.
  
  
 0.835
benC
Benzoate 1,2-dioxygenase electron transfer component [Includes: Ferredoxin; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
  
 0.835
PSEEN5329
Putative oxidoreductase, iron-sulfur-binding; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme.
  
  
 0.835
PSEEN3251
Putative dihydroorotate dehydrogenase, FMN-linked, 4Fe-4S ferredoxin-type protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme.
  
 
 0.833
Your Current Organism:
Pseudomonas entomophila
NCBI taxonomy Id: 384676
Other names: P. entomophila L48, Pseudomonas entomophila L48, Pseudomonas entomophila str. L48, Pseudomonas entomophila strain L48
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