node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PSEEN0432 | glmU | PSEEN0432 | PSEEN5540 | Putative phosphotransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family. | 0.919 |
PSEEN1500 | PSEEN1506 | PSEEN1500 | PSEEN1506 | Putative polysaccharide biosynthesis protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | Putative dTDP-glucose-4,6-dehydratase/UDP-glucose 4-epimerase WbpM; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | 0.953 |
PSEEN1500 | glmU | PSEEN1500 | PSEEN5540 | Putative polysaccharide biosynthesis protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family. | 0.916 |
PSEEN1500 | lpxA | PSEEN1500 | PSEEN4208 | Putative polysaccharide biosynthesis protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | UDP-acetylglucosamine acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.811 |
PSEEN1500 | murA | PSEEN1500 | PSEEN1105 | Putative polysaccharide biosynthesis protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.910 |
PSEEN1500 | wecB | PSEEN1500 | PSEEN2963 | Putative polysaccharide biosynthesis protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | UDP-N-acetyl glucosamine-2-epimerase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the UDP-N-acetylglucosamine 2-epimerase family. | 0.941 |
PSEEN1506 | PSEEN1500 | PSEEN1506 | PSEEN1500 | Putative dTDP-glucose-4,6-dehydratase/UDP-glucose 4-epimerase WbpM; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | Putative polysaccharide biosynthesis protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | 0.953 |
PSEEN1506 | glmU | PSEEN1506 | PSEEN5540 | Putative dTDP-glucose-4,6-dehydratase/UDP-glucose 4-epimerase WbpM; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family. | 0.916 |
PSEEN1506 | wecB | PSEEN1506 | PSEEN2963 | Putative dTDP-glucose-4,6-dehydratase/UDP-glucose 4-epimerase WbpM; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | UDP-N-acetyl glucosamine-2-epimerase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the UDP-N-acetylglucosamine 2-epimerase family. | 0.933 |
glmM | glmS | PSEEN0789 | PSEEN5537 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | Glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.961 |
glmM | glmU | PSEEN0789 | PSEEN5540 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family. | 0.975 |
glmM | murA | PSEEN0789 | PSEEN1105 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.676 |
glmM | prs | PSEEN0789 | PSEEN0857 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | Ribose-phosphate pyrophosphokinase (Phosphoribosyl pyrophosphate synthetase); Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | 0.428 |
glmM | pta | PSEEN0789 | PSEEN0916 | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | 0.420 |
glmS | glmM | PSEEN5537 | PSEEN0789 | Glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family. | 0.961 |
glmS | glmU | PSEEN5537 | PSEEN5540 | Glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family. | 0.948 |
glmS | murA | PSEEN5537 | PSEEN1105 | Glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.444 |
glmS | pta | PSEEN5537 | PSEEN0916 | Glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. | 0.450 |
glmU | PSEEN0432 | PSEEN5540 | PSEEN0432 | UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family. | Putative phosphotransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | 0.919 |
glmU | PSEEN1500 | PSEEN5540 | PSEEN1500 | UDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family. | Putative polysaccharide biosynthesis protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | 0.916 |