STRINGSTRING
ADU35470.1 ADU35470.1 ADU35468.1 ADU35468.1 ADU35469.1 ADU35469.1 hisC-2 hisC-2 hisB hisB hisH hisH murA murA hisG hisG hisD hisD ADU35464.1 ADU35464.1 hisA hisA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
ADU35470.1KEGG: pap:PSPA7_0336 hypothetical protein. (221 aa)    
Predicted Functional Partners:
ADU35468.1
KEGG: ctt:CtCNB1_0713 hypothetical protein.
       0.773
ADU35469.1
KEGG: vap:Vapar_1166 hypothetical protein.
       0.773
hisC-2
KEGG: vap:Vapar_1167 histidinol-phosphate aminotransferase; TIGRFAM: histidinol-phosphate aminotransferase; PFAM: aminotransferase class I and II; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
       0.773
hisB
KEGG: vap:Vapar_1168 imidazoleglycerol-phosphate dehydratase; PFAM: imidazoleglycerol-phosphate dehydratase.
       0.773
hisH
Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
       0.714
murA
UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.
       0.648
hisG
ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily.
       0.648
hisD
Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.
       0.648
ADU35464.1
PFAM: BolA family protein; KEGG: vap:Vapar_1162 BolA family protein; Belongs to the BolA/IbaG family.
       0.543
hisA
TIGRFAM: phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; KEGG: vap:Vapar_1170 phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; PFAM: histidine biosynthesis protein.
       0.542
Your Current Organism:
Variovorax paradoxus EPS
NCBI taxonomy Id: 595537
Other names: V. paradoxus EPS, Variovorax paradoxus str. EPS, Variovorax paradoxus strain EPS
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