STRINGSTRING
ADV28443.1 ADV28443.1 ADV28445.1 ADV28445.1 ADV27894.1 ADV27894.1 ADV25917.1 ADV25917.1 ADV26615.1 ADV26615.1 ADV27885.1 ADV27885.1 ADV28138.1 ADV28138.1 ADV25916.1 ADV25916.1 thyA thyA ADV25866.1 ADV25866.1 dut dut
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Neighborhood
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[Homology]
Score
ADV28443.1KEGG: pap:PSPA7_6297 hypothetical protein. (258 aa)    
Predicted Functional Partners:
ADV28445.1
Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.
   
 0.987
ADV27894.1
PFAM: protein of unknown function DUF179; KEGG: xal:XALc_2157 hypothetical protein; Belongs to the UPF0301 (AlgH) family.
   
 0.946
ADV25917.1
Ribonucleotide reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family.
  
 
 0.937
ADV26615.1
PFAM: glutaredoxin 2; KEGG: xal:XALc_2178 putative thiol-disulfide isomerase and thioredoxin; glutaredoxin protein.
  
 0.783
ADV27885.1
Glutaredoxin 3; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins.
  
 0.783
ADV28138.1
PFAM: glutaredoxin; KEGG: pmy:Pmen_3551 glutaredoxin.
  
 0.783
ADV25916.1
Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
    
 0.687
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
  
  
 0.620
ADV25866.1
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
   
 
 0.611
dut
Deoxyuridine 5'-triphosphate nucleotidohydrolase Dut; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family.
  
  
 0.585
Your Current Organism:
Pseudoxanthomonas suwonensis 111
NCBI taxonomy Id: 743721
Other names: P. suwonensis 11-1, Pseudoxanthomonas suwonensis 11-1, Pseudoxanthomonas suwonensis str. 11-1, Pseudoxanthomonas suwonensis strain 11-1
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