STRINGSTRING
cobB-3 cobB-3 nadD nadD nadE nadE nadK nadK sthA sthA ACA72746.1 ACA72746.1 ACA72465.1 ACA72465.1 nudC nudC ACA75546.1 ACA75546.1 ACA75547.1 ACA75547.1 cobB cobB
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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Score
cobB-3PFAM: Silent information regulator protein Sir2; KEGG: psp:PSPPH_4322 NAD-dependent deacetylase 4 (regulatory protein SIR2homolog 4); Belongs to the sirtuin family. Class III subfamily. (252 aa)    
Predicted Functional Partners:
nadD
Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
   
 0.922
nadE
NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
    
 0.921
nadK
ATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
  
 
 0.918
sthA
Pyridine nucleotide-disulphide oxidoreductase dimerisation region; Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
  
 0.912
ACA72746.1
Nicotinamidase; KEGG: pen:PSEEN2059 nicotinamidase.
  
 0.912
ACA72465.1
PFAM: Inosine/uridine-preferring nucleoside hydrolase; KEGG: pen:PSEEN1958 inosine-uridine preferring nucleoside hydrolase; Belongs to the IUNH family.
   
 
 0.908
nudC
PFAM: NUDIX hydrolase; NADH pyrophosphatase-like; Zinc ribbon NADH pyrophosphatase; KEGG: pen:PSEEN2184 NTP pyrophosphohydrolase.
    
 0.907
ACA75546.1
NAD(P)(+) transhydrogenase (AB-specific); PFAM: alanine dehydrogenase/PNT domain protein; KEGG: pen:PSEEN0116 proton-translocating NAD(P) transhydrogenase.
     
 0.907
ACA75547.1
KEGG: pen:PSEEN0115 pyridine proton-translocating NAD(P) transhydrogenase.
     
 0.906
cobB
PFAM: Silent information regulator protein Sir2; thiamine pyrophosphate protein central region; KEGG: pst:PSPTO_4675 transcriptional regulator, Sir2 family; Belongs to the sirtuin family. Class III subfamily.
  
  
 
0.902
Your Current Organism:
Pseudomonas putida W619
NCBI taxonomy Id: 390235
Other names: P. putida W619, Pseudomonas putida str. W619, Pseudomonas putida strain W619
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