STRINGSTRING
hopAS1 hopAS1 ABD93120.1 ABD93120.1 AAO55332.1 AAO55332.1 polI polI hopR1 hopR1 hopY1 hopY1 gyrB gyrB parE parE hopI1 hopI1 hopAO1 hopAO1 topA topA
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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hopAS1Type III effector HopAS1; This region contains an authentic point mutation causing a premature stop and is not the result of a sequencing artifact; identified by sequence similarity to the N-terminal regions of HopAS1 in Pseudomonas syringae phaseolicola; previously known as ORF01152 (PMID11854524; Fouts et al, 2002). (279 aa)    
Predicted Functional Partners:
ABD93120.1
Conserved hypothetical protein; Similar to gene downstream of PSPPH4735.
       0.651
AAO55332.1
Conserved protein of unknown function; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.
  
 
 0.611
polI
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 
 0.592
hopR1
Type III effector HopR1; Previously known as HolPtoR; see PMID:20190049 for expression data; similar to GP:17431754, and GP:19071522; identified by sequence similarity; putative.
      
 0.459
hopY1
Type III effector HopY1; Previously known as HolPtoY (PMID11872842; Guttman et al, 2002) and ORF11 (PMID11854524; Fouts et al, 2002); similar to GP:19071534; identified by sequence similarity; putative; see PMID:20190049 for expression data; Previously known as HolPtoY; PMID1187284, Guttman et al, 2002; and ORF11; PMID11854524, Fouts et al, 2002; ., see PMID:20190049 for expression data; similar to GP:19071534, identified by sequence similarity, putative.
  
 
 0.457
gyrB
DNA gyrase, subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
   
 
 0.448
parE
DNA topoisomerase IV, B subunit; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily.
   
 
 0.448
hopI1
Type III effector HopI1; Previously known as HopPmaI (PMID11872842; Guttman et al, 2002); see PMID:20190049 for expression data; similar to GP:19071496; identified by sequence similarity; putative.
    
 
 0.447
hopAO1
Type III effector HopAO1; Effector showing tyrosine-phosphatase activity required for host defense suppression. Functions inside plant cells causing suppression of HR (hypersensitive response), PR1 gene expression and oxidative burst probably by interfering with a MAPK (mitogen-activated protein kinase) pathway. MAPK cascades are known to activate defense- related transcription factors. Inhibits plant pattern-recognition receptors (PRRs) activation.
    
 
 0.443
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
 
 0.431
Your Current Organism:
Pseudomonas syringae tomato
NCBI taxonomy Id: 223283
Other names: P. syringae pv. tomato str. DC3000, Pseudomonas syringae DC3000, Pseudomonas syringae pv. tomato DC3000, Pseudomonas syringae pv. tomato str. ATCC BAA-871, Pseudomonas syringae pv. tomato str. DC3000
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