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pqqF pqqF pqqE pqqE pqqC pqqC pqqD pqqD pqqB pqqB AAO53673.1 AAO53673.1 AAO54051.1 AAO54051.1 pqqA pqqA AAO54058.1 AAO54058.1 prlC prlC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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pqqFCoenzyme PQQ synthesis protein F; Required for coenzyme pyrroloquinoline quinone (PQQ) biosynthesis. It is thought that this protein is a protease that cleaves peptides bond in a small peptide (gene pqqA), providing the glutamate and tyrosine residues which are necessary for the synthesis of PQQ (By similarity). (779 aa)    
Predicted Functional Partners:
pqqE
Coenzyme PQQ synthesis protein E; Catalyzes the cross-linking of a glutamate residue and a tyrosine residue in the PqqA protein as part of the biosynthesis of pyrroloquinoline quinone (PQQ).
 
   
 0.732
pqqC
Coenzyme PQQ synthesis protein C; Ring cyclization and eight-electron oxidation of 3a-(2-amino- 2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9- dicarboxylic-acid to PQQ.
 
   
 0.716
pqqD
Coenzyme PQQ synthesis protein D; Functions as a PqqA binding protein and presents PqqA to PqqE, in the pyrroloquinoline quinone (PQQ) biosynthetic pathway.
     
 0.710
pqqB
Coenzyme PQQ synthesis protein B; May be involved in the transport of PQQ or its precursor to the periplasm; Belongs to the PqqB family.
     
 0.704
AAO53673.1
Peptidase, M16 family; Identified by match to PFAM protein family HMM PF00675.
  
 
 0.573
AAO54051.1
Conserved protein of unknown function; See PMID:20190049 for expression data.
  
  
 0.539
pqqA
Coenzyme PQQ synthesis protein A; Required for coenzyme pyrroloquinoline quinone (PQQ) biosynthesis. PQQ is probably formed by cross-linking a specific glutamate to a specific tyrosine residue and excising these residues from the peptide (By similarity); Belongs to the PqqA family.
       0.528
AAO54058.1
ISPsy8, transposase OrfA; Similar to GP:17428452; identified by sequence similarity; putative.
       0.483
prlC
Similar to SP:P27298; identified by sequence similarity; putative; see PMID:20190049 for expression data; similar to SP:P27298, identified by sequence similarity, putative.
   
 
 0.425
Your Current Organism:
Pseudomonas syringae tomato
NCBI taxonomy Id: 223283
Other names: P. syringae pv. tomato str. DC3000, Pseudomonas syringae DC3000, Pseudomonas syringae pv. tomato DC3000, Pseudomonas syringae pv. tomato str. ATCC BAA-871, Pseudomonas syringae pv. tomato str. DC3000
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