node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AAO53767.1 | AAO54375.1 | PSPTO_0221 | PSPTO_0835 | HAD-superfamily hydrolase; See PMID:20190049 for expression data; identified by match to TIGR protein family HMM TIGR01691. | ribD C-terminal domain protein; See PMID:20190049 for expression data; similar to GB:S69136, GB:S69198, GB:M28594, and PID:292763; identified by sequence similarity; putative. | 0.904 |
AAO53767.1 | ribD | PSPTO_0221 | PSPTO_0690 | HAD-superfamily hydrolase; See PMID:20190049 for expression data; identified by match to TIGR protein family HMM TIGR01691. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.926 |
AAO53767.1 | ribE | PSPTO_0221 | PSPTO_0691 | HAD-superfamily hydrolase; See PMID:20190049 for expression data; identified by match to TIGR protein family HMM TIGR01691. | Riboflavin synthase, alpha subunit; See PMID:20190049 for expression data. | 0.904 |
AAO53767.1 | ribH-1 | PSPTO_0221 | PSPTO_0693 | HAD-superfamily hydrolase; See PMID:20190049 for expression data; identified by match to TIGR protein family HMM TIGR01691. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family. | 0.903 |
AAO53767.1 | ribH-2 | PSPTO_0221 | PSPTO_1839 | HAD-superfamily hydrolase; See PMID:20190049 for expression data; identified by match to TIGR protein family HMM TIGR01691. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family. | 0.903 |
AAO54375.1 | AAO53767.1 | PSPTO_0835 | PSPTO_0221 | ribD C-terminal domain protein; See PMID:20190049 for expression data; similar to GB:S69136, GB:S69198, GB:M28594, and PID:292763; identified by sequence similarity; putative. | HAD-superfamily hydrolase; See PMID:20190049 for expression data; identified by match to TIGR protein family HMM TIGR01691. | 0.904 |
AAO54375.1 | ribA | PSPTO_0835 | PSPTO_0696 | ribD C-terminal domain protein; See PMID:20190049 for expression data; similar to GB:S69136, GB:S69198, GB:M28594, and PID:292763; identified by sequence similarity; putative. | GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. | 0.831 |
AAO54375.1 | ribBA-1 | PSPTO_0835 | PSPTO_0692 | ribD C-terminal domain protein; See PMID:20190049 for expression data; similar to GB:S69136, GB:S69198, GB:M28594, and PID:292763; identified by sequence similarity; putative. | 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.959 |
AAO54375.1 | ribBA-2 | PSPTO_0835 | PSPTO_2668 | ribD C-terminal domain protein; See PMID:20190049 for expression data; similar to GB:S69136, GB:S69198, GB:M28594, and PID:292763; identified by sequence similarity; putative. | 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the N-terminal section; belongs to the DHBP synthase family. | 0.959 |
AAO54375.1 | ribD | PSPTO_0835 | PSPTO_0690 | ribD C-terminal domain protein; See PMID:20190049 for expression data; similar to GB:S69136, GB:S69198, GB:M28594, and PID:292763; identified by sequence similarity; putative. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.933 |
AAO54375.1 | ribE | PSPTO_0835 | PSPTO_0691 | ribD C-terminal domain protein; See PMID:20190049 for expression data; similar to GB:S69136, GB:S69198, GB:M28594, and PID:292763; identified by sequence similarity; putative. | Riboflavin synthase, alpha subunit; See PMID:20190049 for expression data. | 0.931 |
AAO54375.1 | ribH-1 | PSPTO_0835 | PSPTO_0693 | ribD C-terminal domain protein; See PMID:20190049 for expression data; similar to GB:S69136, GB:S69198, GB:M28594, and PID:292763; identified by sequence similarity; putative. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family. | 0.867 |
AAO54375.1 | ribH-2 | PSPTO_0835 | PSPTO_1839 | ribD C-terminal domain protein; See PMID:20190049 for expression data; similar to GB:S69136, GB:S69198, GB:M28594, and PID:292763; identified by sequence similarity; putative. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family. | 0.724 |
AAO54375.1 | thiL | PSPTO_0835 | PSPTO_0695 | ribD C-terminal domain protein; See PMID:20190049 for expression data; similar to GB:S69136, GB:S69198, GB:M28594, and PID:292763; identified by sequence similarity; putative. | Thiamine monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. | 0.409 |
nusB | ribA | PSPTO_0694 | PSPTO_0696 | N utilization substance protein B; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. | GTP cyclohydrolase II; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. | 0.646 |
nusB | ribBA-1 | PSPTO_0694 | PSPTO_0692 | N utilization substance protein B; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. | 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.810 |
nusB | ribBA-2 | PSPTO_0694 | PSPTO_2668 | N utilization substance protein B; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. | 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the N-terminal section; belongs to the DHBP synthase family. | 0.641 |
nusB | ribD | PSPTO_0694 | PSPTO_0690 | N utilization substance protein B; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.775 |
nusB | ribE | PSPTO_0694 | PSPTO_0691 | N utilization substance protein B; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. | Riboflavin synthase, alpha subunit; See PMID:20190049 for expression data. | 0.526 |
nusB | ribH-1 | PSPTO_0694 | PSPTO_0693 | N utilization substance protein B; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin; Belongs to the DMRL synthase family. | 0.928 |