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AAO54296.1 AAO54296.1 cfa6 cfa6 AAO54297.1 AAO54297.1 AAO57967.1 AAO57967.1 cmaA cmaA AAO56423.1 AAO56423.1 cfa7 cfa7 AAO56529.1 AAO56529.1 AAO57169.1 AAO57169.1
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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AAO54296.1Alcohol dehydrogenase, zinc-containing protein; See PMID:20190049 for expression data; similar to GP:15073967; identified by sequence similarity; putative; Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily. (349 aa)    
Predicted Functional Partners:
cfa6
Coronafacic acid polyketide synthase I; This gene is the first of two multimodular polyketide synthetases involved in the biosynthesis of coronafacic acid. This synthetase is proposed to receive CPC (2-carboxy-2-cyclopentenone) from an acyl carrier protein (cfa1), it then adds a buyrate group and then completely reduces the ketone of the (former) carboxylate group. The resulting product is then passed to the second polyketide synthetase (cfa7); similar to GP:13346874; identified by sequence similarity; putative; see PMID:20190049 for expression data; This gene is the first of two multi [...]
  
 
0.643
AAO54297.1
Transcriptional regulator, LysR family; Identified by match to PFAM protein family HMM PF00126; Belongs to the LysR transcriptional regulatory family.
       0.600
AAO57967.1
This gene is aparrently the terminal component of a non-ribosomal peptide synthetase (due to the presence of the terminal thioesterase domain) and is most likely associated with the previous gene which appears to be a initiating component. This gene contains three complete amino acid activation, thiolation and condensation domain modules and appears to be specific for glycine, an unidentified amino acid and serine according to the prediction algorithm at http://raynam.chm.jhu.edu/; nrps/index2.html. Taken together these two genes appear to direct the biosynthesis of a previously undesc [...]
  
  
 0.558
cmaA
Coronamic acid synthetase CmaA; Non-ribosomal peptide synthetase with adenylation and thiolation domains; reacts with the AMP derivative of L-allo-isoleucine to produce an aminoacyl thiolester intermediate during coronamic acid biosynthesis; see PMID: 14679222; see PMID:20190049 for expression data; non-ribosomal peptide synthetase with adenylation and thiolation domains, reacts with the AMP derivative of L-allo-isoleucine to produce an aminoacyl thiolester intermediate during coronamic acid biosynthesis, see PMID: 14679222.
  
  
 0.558
AAO56423.1
Conserved protein of unknown function; Identified by match to PFAM protein family HMM PF02619; see PMID:20190049 for expression data; identified by match to PFAM protein family HMM PF02619.
 
    0.502
cfa7
Coronafacic acid polyketide synthetase II; This gene is the second of two multimodular polyketide synthetases involved in the biosynthesis of coronafacic acid. This synthetase is proposed to receive CPE (2-[1-oxo-2-cyclopenten-2-ylmethyl]butanoic acid) from the first synthetase, Cpe6. It then adds one final acetate group, catalyzes the cyclization of the second ring and converts a ketone to a double bond. The product is released by a terminal thioesterase domain; similar to GP:13162634; identified by sequence similarity; putative; see PMID:20190049 for expression data; This gene is the [...]
   
 
 0.497
AAO56529.1
Alcohol dehydrogenase, zinc-containing protein; See PMID:20190049 for expression data; similar to GP:13926036; identified by sequence similarity; putative.
  
     0.452
AAO57169.1
Oxidoreductase, aldo/keto reductase family; See PMID:20190049 for expression data; identified by match to TIGR protein family HMM TIGR01293.
 
  
 0.407
Your Current Organism:
Pseudomonas syringae tomato
NCBI taxonomy Id: 223283
Other names: P. syringae pv. tomato str. DC3000, Pseudomonas syringae DC3000, Pseudomonas syringae pv. tomato DC3000, Pseudomonas syringae pv. tomato str. ATCC BAA-871, Pseudomonas syringae pv. tomato str. DC3000
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