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ilvE ilvE leuA leuA ilvD ilvD hom hom panB panB AAO55299.1 AAO55299.1 gshA gshA ilvA-1 ilvA-1 ilvA-2 ilvA-2 thrB thrB AAO55795.1 AAO55795.1
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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ilvEBranched-chain amino acid aminotransferase; Identified by match to TIGR protein family HMM TIGR01121; see PMID:20190049 for expression data; identified by match to TIGR protein family HMM TIGR01121. (339 aa)    
Predicted Functional Partners:
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
  
 0.983
ilvD
Dihydroxy-acid dehydratase; Similar to SP:P05791; identified by sequence similarity; putative; see PMID:20190049 for expression data; similar to SP:P05791, identified by sequence similarity, putative; Belongs to the IlvD/Edd family.
  
 0.967
hom
Homoserine dehydrogenase; See PMID:20190049 for expression data.
  
 0.961
panB
3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.
    
 0.922
AAO55299.1
Aminotransferase, classes I and II; See PMID:20190049 for expression data.
    
 0.909
gshA
Glutamate--cysteine ligase; See PMID:20190049 for expression data; Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.
     
  0.900
ilvA-1
Threonine dehydratase, biosynthetic; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
  
 
 0.886
ilvA-2
Threonine dehydratase, biosynthetic; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
  
 
 0.886
thrB
Homoserine kinase; See PMID:20190049 for expression data; identified by match to PFAM protein family HMM PF01636; Belongs to the pseudomonas-type ThrB family.
     
 0.815
AAO55795.1
Hydrolase, haloacid dehalogenase-like family; Phosphoserine phosphatase that mediates dephosphorylation of phospho-serine in the serine biosynthesis pathway. Also able to dephosphorylate phospho-threonine.
    
 0.812
Your Current Organism:
Pseudomonas syringae tomato
NCBI taxonomy Id: 223283
Other names: P. syringae pv. tomato str. DC3000, Pseudomonas syringae DC3000, Pseudomonas syringae pv. tomato DC3000, Pseudomonas syringae pv. tomato str. ATCC BAA-871, Pseudomonas syringae pv. tomato str. DC3000
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