node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AAO54949.1 | AAO54950.1 | PSPTO_1428 | PSPTO_1429 | Ferredoxin, 2Fe-2S; See PMID:20190049 for expression data. | Conserved protein of unknown function; See PMID:20190049 for expression data. | 0.994 |
AAO54949.1 | cyaY | PSPTO_1428 | PSPTO_0227 | Ferredoxin, 2Fe-2S; See PMID:20190049 for expression data. | cyaY protein; Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis. | 0.847 |
AAO54949.1 | hscA | PSPTO_1428 | PSPTO_1427 | Ferredoxin, 2Fe-2S; See PMID:20190049 for expression data. | Chaperone protein HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. | 0.983 |
AAO54949.1 | hscB | PSPTO_1428 | PSPTO_1426 | Ferredoxin, 2Fe-2S; See PMID:20190049 for expression data. | Co-chaperone Hsc20; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family. | 0.986 |
AAO54949.1 | iscA | PSPTO_1428 | PSPTO_1425 | Ferredoxin, 2Fe-2S; See PMID:20190049 for expression data. | Iron-binding protein IscA; Is able to transfer iron-sulfur clusters to apo-ferredoxin. Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system; Belongs to the HesB/IscA family. | 0.961 |
AAO54949.1 | iscS-1 | PSPTO_1428 | PSPTO_0272 | Ferredoxin, 2Fe-2S; See PMID:20190049 for expression data. | Cysteine desulfurase; Similar to SP:P39171, GB:D90244, and PID:216809; identified by sequence similarity; putative. | 0.844 |
AAO54949.1 | iscS-2 | PSPTO_1428 | PSPTO_1423 | Ferredoxin, 2Fe-2S; See PMID:20190049 for expression data. | Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily. | 0.943 |
AAO54949.1 | iscS-3 | PSPTO_1428 | PSPTO_3438 | Ferredoxin, 2Fe-2S; See PMID:20190049 for expression data. | Cysteine desulfurase; See PMID:20190049 for expression data; similar to SP:P39171, GB:D90244, and PID:216809; identified by sequence similarity; putative. | 0.851 |
AAO54949.1 | iscU | PSPTO_1428 | PSPTO_1424 | Ferredoxin, 2Fe-2S; See PMID:20190049 for expression data. | Iron-binding protein IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | 0.987 |
AAO54949.1 | nuoCD | PSPTO_1428 | PSPTO_3367 | Ferredoxin, 2Fe-2S; See PMID:20190049 for expression data. | NADH dehydrogenase I, C/D subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 30 kDa subunit family. | 0.931 |
AAO54950.1 | AAO54949.1 | PSPTO_1429 | PSPTO_1428 | Conserved protein of unknown function; See PMID:20190049 for expression data. | Ferredoxin, 2Fe-2S; See PMID:20190049 for expression data. | 0.994 |
AAO54950.1 | cyaY | PSPTO_1429 | PSPTO_0227 | Conserved protein of unknown function; See PMID:20190049 for expression data. | cyaY protein; Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis. | 0.728 |
AAO54950.1 | hscA | PSPTO_1429 | PSPTO_1427 | Conserved protein of unknown function; See PMID:20190049 for expression data. | Chaperone protein HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. | 0.951 |
AAO54950.1 | hscB | PSPTO_1429 | PSPTO_1426 | Conserved protein of unknown function; See PMID:20190049 for expression data. | Co-chaperone Hsc20; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family. | 0.972 |
AAO54950.1 | iscA | PSPTO_1429 | PSPTO_1425 | Conserved protein of unknown function; See PMID:20190049 for expression data. | Iron-binding protein IscA; Is able to transfer iron-sulfur clusters to apo-ferredoxin. Multiple cycles of [2Fe2S] cluster formation and transfer are observed, suggesting that IscA acts catalytically. Recruits intracellular free iron so as to provide iron for the assembly of transient iron-sulfur cluster in IscU in the presence of IscS, L-cysteine and the thioredoxin reductase system; Belongs to the HesB/IscA family. | 0.900 |
AAO54950.1 | iscS-1 | PSPTO_1429 | PSPTO_0272 | Conserved protein of unknown function; See PMID:20190049 for expression data. | Cysteine desulfurase; Similar to SP:P39171, GB:D90244, and PID:216809; identified by sequence similarity; putative. | 0.601 |
AAO54950.1 | iscS-2 | PSPTO_1429 | PSPTO_1423 | Conserved protein of unknown function; See PMID:20190049 for expression data. | Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily. | 0.855 |
AAO54950.1 | iscS-3 | PSPTO_1429 | PSPTO_3438 | Conserved protein of unknown function; See PMID:20190049 for expression data. | Cysteine desulfurase; See PMID:20190049 for expression data; similar to SP:P39171, GB:D90244, and PID:216809; identified by sequence similarity; putative. | 0.604 |
AAO54950.1 | iscU | PSPTO_1429 | PSPTO_1424 | Conserved protein of unknown function; See PMID:20190049 for expression data. | Iron-binding protein IscU; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | 0.936 |
cyaY | AAO54949.1 | PSPTO_0227 | PSPTO_1428 | cyaY protein; Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis. | Ferredoxin, 2Fe-2S; See PMID:20190049 for expression data. | 0.847 |