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mnmC mnmC soxA-1 soxA-1 AAO55160.1 AAO55160.1 rlmN rlmN AAO55712.1 AAO55712.1 smtA smtA thiI thiI selU selU soxA-2 soxA-2 AAO55156.1 AAO55156.1 AAO55158.1 AAO55158.1
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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experimentally determined
Predicted Interactions
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gene co-occurrence
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textmining
co-expression
protein homology
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mnmCOxidoreductase, FAD-binding protein; Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34; In the N-terminal section; belongs to the methyltransferase superfamily. tRNA (mnm(5)s(2)U34)-methyltransferase family. (660 aa)    
Predicted Functional Partners:
soxA-1
Sarcosine oxidase, alpha subunit; Similar to SP:Q46337; identified by sequence similarity; putative; Belongs to the GcvT family.
  
 
 0.751
AAO55160.1
Conserved hypothetical protein; Uses inorganic polyphosphate (polyP) as a donor to convert AMP to ADP. Can also convert GMP to GDP, with lower efficiency. Belongs to the polyphosphate kinase 2 (PPK2) family. Class II subfamily.
       0.619
rlmN
Radical SAM enzyme, Cfr family; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family.
 
   
 0.540
AAO55712.1
Succinate dehydrogenase, hydrophobic membrane anchor protein; Membrane-anchoring subunit of succinate dehydrogenase (SDH).
  
    0.519
smtA
smtA protein; See PMID:20190049 for expression data.
  
 
 
 0.518
thiI
Thiamin biosynthesis protein ThiI; Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS.
 
   
 0.509
selU
Conserved hypothetical protein; Involved in the post-transcriptional modification of the uridine at the wobble position (U34) of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Catalyzes the conversion of 2-thiouridine (S2U-RNA) to 2- selenouridine (Se2U-RNA). Acts in a two-step process involving geranylation of 2-thiouridine (S2U) to S-geranyl-2-thiouridine (geS2U) and subsequent selenation of the latter derivative to 2-selenouridine (Se2U) in the tRNA chain.
  
   
 0.490
soxA-2
Sarcosine oxidase, alpha subunit; Similar to SP:Q46337; identified by sequence similarity; putative; Belongs to the GcvT family.
  
 
 0.490
AAO55156.1
Conserved hypothetical protein.
       0.485
AAO55158.1
ABC transporter, ATP-binding protein; See PMID:20190049 for expression data.
       0.485
Your Current Organism:
Pseudomonas syringae tomato
NCBI taxonomy Id: 223283
Other names: P. syringae pv. tomato str. DC3000, Pseudomonas syringae DC3000, Pseudomonas syringae pv. tomato DC3000, Pseudomonas syringae pv. tomato str. ATCC BAA-871, Pseudomonas syringae pv. tomato str. DC3000
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