STRINGSTRING
pobR pobR pcaQ pcaQ vanR vanR pobA pobA lrp lrp pcaG pcaG AAO57967.1 AAO57967.1 cmaA cmaA cfa6 cfa6 pcaH pcaH rpoH rpoH
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pobRTranscriptional regulator PobR. (289 aa)    
Predicted Functional Partners:
pcaQ
Pca operon transcriptional activator PcaQ; See PMID:20190049 for expression data; similar to GP:10442737, and SP:P52668; identified by sequence similarity; putative; Belongs to the LysR transcriptional regulatory family.
 
  
 0.939
vanR
Transcriptional regulator VanR; See PMID:20190049 for expression data.
 
  
 0.881
pobA
P-hydroxybenzoate hydroxylase.
 
   
 0.877
lrp
Leucine-responsive regulatory protein; See PMID:20190049 for expression data; similar to SP:P37403; identified by sequence similarity; putative.
   
  
 0.712
pcaG
Protocatechuate 3,4-dioxygenase, alpha subunit; See PMID:20190049 for expression data; similar to GP:10442739, and SP:P00436; identified by sequence similarity; putative.
 
   
 0.638
AAO57967.1
This gene is aparrently the terminal component of a non-ribosomal peptide synthetase (due to the presence of the terminal thioesterase domain) and is most likely associated with the previous gene which appears to be a initiating component. This gene contains three complete amino acid activation, thiolation and condensation domain modules and appears to be specific for glycine, an unidentified amino acid and serine according to the prediction algorithm at http://raynam.chm.jhu.edu/; nrps/index2.html. Taken together these two genes appear to direct the biosynthesis of a previously undesc [...]
     
 0.630
cmaA
Coronamic acid synthetase CmaA; Non-ribosomal peptide synthetase with adenylation and thiolation domains; reacts with the AMP derivative of L-allo-isoleucine to produce an aminoacyl thiolester intermediate during coronamic acid biosynthesis; see PMID: 14679222; see PMID:20190049 for expression data; non-ribosomal peptide synthetase with adenylation and thiolation domains, reacts with the AMP derivative of L-allo-isoleucine to produce an aminoacyl thiolester intermediate during coronamic acid biosynthesis, see PMID: 14679222.
     
 0.630
cfa6
Coronafacic acid polyketide synthase I; This gene is the first of two multimodular polyketide synthetases involved in the biosynthesis of coronafacic acid. This synthetase is proposed to receive CPC (2-carboxy-2-cyclopentenone) from an acyl carrier protein (cfa1), it then adds a buyrate group and then completely reduces the ketone of the (former) carboxylate group. The resulting product is then passed to the second polyketide synthetase (cfa7); similar to GP:13346874; identified by sequence similarity; putative; see PMID:20190049 for expression data; This gene is the first of two multi [...]
  
  
 0.608
pcaH
Protocatechuate 3,4-dioxygenase, beta subunit; Similar to SP:P00437, GB:M30496, SP:P15374, and PID:340074; identified by sequence similarity; putative.
 
   
 0.602
rpoH
RNA polymerase sigma-32 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes.
    
 
 0.556
Your Current Organism:
Pseudomonas syringae tomato
NCBI taxonomy Id: 223283
Other names: P. syringae pv. tomato str. DC3000, Pseudomonas syringae DC3000, Pseudomonas syringae pv. tomato DC3000, Pseudomonas syringae pv. tomato str. ATCC BAA-871, Pseudomonas syringae pv. tomato str. DC3000
Server load: low (12%) [HD]