node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AAO54220.1 | lolD | PSPTO_0678 | PSPTO_2110 | NAD-dependent epimerase/dehydratase family protein; See PMID:20190049 for expression data. | Lipoprotein releasing system, ATP-binding protein LolD; Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner. | 0.589 |
AAO54220.1 | rpsK | PSPTO_0678 | PSPTO_0649 | NAD-dependent epimerase/dehydratase family protein; See PMID:20190049 for expression data. | Ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family. | 0.568 |
AAO55157.1 | lolA | PSPTO_1637 | PSPTO_3348 | ABC transporter, permease protein, putative. | Outer membrane lipoprotein carrier protein; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane). | 0.565 |
AAO55157.1 | lolD | PSPTO_1637 | PSPTO_2110 | ABC transporter, permease protein, putative. | Lipoprotein releasing system, ATP-binding protein LolD; Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner. | 0.600 |
AAO55157.1 | macB1 | PSPTO_1637 | PSPTO_2159 | ABC transporter, permease protein, putative. | Macrolide ABC efflux protein; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | 0.723 |
AAO55157.1 | syfD | PSPTO_1637 | PSPTO_2832 | ABC transporter, permease protein, putative. | Syringafactin efflux protein SyfD; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | 0.723 |
ADD53003.1 | lolC | PSPTO_2108 | PSPTO_2109 | Protein of unknown function; PMID:20190049. | Lipoprotein releasing system transmembrane protein LolC; See PMID:20190049 for expression data. | 0.578 |
ADD53003.1 | lolD | PSPTO_2108 | PSPTO_2110 | Protein of unknown function; PMID:20190049. | Lipoprotein releasing system, ATP-binding protein LolD; Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner. | 0.592 |
ADD53003.1 | lolE | PSPTO_2108 | PSPTO_2111 | Protein of unknown function; PMID:20190049. | Lipoprotein releasing system transmembrane protein LolE; See PMID:20190049 for expression data. | 0.507 |
ksgA | lolD | PSPTO_0551 | PSPTO_2110 | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | Lipoprotein releasing system, ATP-binding protein LolD; Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner. | 0.606 |
ksgA | macB1 | PSPTO_0551 | PSPTO_2159 | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | Macrolide ABC efflux protein; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | 0.568 |
ksgA | rpsK | PSPTO_0551 | PSPTO_0649 | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | Ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family. | 0.894 |
ksgA | syfD | PSPTO_0551 | PSPTO_2832 | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | Syringafactin efflux protein SyfD; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | 0.568 |
lolA | AAO55157.1 | PSPTO_3348 | PSPTO_1637 | Outer membrane lipoprotein carrier protein; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane). | ABC transporter, permease protein, putative. | 0.565 |
lolA | lolC | PSPTO_3348 | PSPTO_2109 | Outer membrane lipoprotein carrier protein; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane). | Lipoprotein releasing system transmembrane protein LolC; See PMID:20190049 for expression data. | 0.830 |
lolA | lolD | PSPTO_3348 | PSPTO_2110 | Outer membrane lipoprotein carrier protein; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane). | Lipoprotein releasing system, ATP-binding protein LolD; Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner. | 0.699 |
lolA | lolE | PSPTO_3348 | PSPTO_2111 | Outer membrane lipoprotein carrier protein; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane). | Lipoprotein releasing system transmembrane protein LolE; See PMID:20190049 for expression data. | 0.829 |
lolA | macB1 | PSPTO_3348 | PSPTO_2159 | Outer membrane lipoprotein carrier protein; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane). | Macrolide ABC efflux protein; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | 0.478 |
lolA | syfD | PSPTO_3348 | PSPTO_2832 | Outer membrane lipoprotein carrier protein; Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane). | Syringafactin efflux protein SyfD; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides. | 0.478 |
lolC | ADD53003.1 | PSPTO_2109 | PSPTO_2108 | Lipoprotein releasing system transmembrane protein LolC; See PMID:20190049 for expression data. | Protein of unknown function; PMID:20190049. | 0.578 |