node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AAO54286.1 | acs | PSPTO_0744 | PSPTO_1825 | Thiolase family protein; Belongs to the thiolase-like superfamily. Thiolase family. | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.934 |
AAO54286.1 | glcB-1 | PSPTO_0744 | PSPTO_0480 | Thiolase family protein; Belongs to the thiolase-like superfamily. Thiolase family. | Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. | 0.922 |
AAO54286.1 | glcB-2 | PSPTO_0744 | PSPTO_3559 | Thiolase family protein; Belongs to the thiolase-like superfamily. Thiolase family. | Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. | 0.922 |
AAO54286.1 | prpB | PSPTO_0744 | PSPTO_2287 | Thiolase family protein; Belongs to the thiolase-like superfamily. Thiolase family. | Methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family. | 0.824 |
AAO54286.1 | sucC | PSPTO_0744 | PSPTO_2202 | Thiolase family protein; Belongs to the thiolase-like superfamily. Thiolase family. | succinyl-CoA synthase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.826 |
AAO54286.1 | sucD | PSPTO_0744 | PSPTO_2203 | Thiolase family protein; Belongs to the thiolase-like superfamily. Thiolase family. | succinyl-CoA synthase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.829 |
AAO55800.1 | AAO55804.1 | PSPTO_2286 | PSPTO_2290 | Transcriptional regulator, GntR family; See PMID:20190049 for expression data. | Conserved hypothetical protein. | 0.519 |
AAO55800.1 | prpB | PSPTO_2286 | PSPTO_2287 | Transcriptional regulator, GntR family; See PMID:20190049 for expression data. | Methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family. | 0.845 |
AAO55800.1 | prpC | PSPTO_2286 | PSPTO_2288 | Transcriptional regulator, GntR family; See PMID:20190049 for expression data. | 2-methylcitrate synthase; See PMID:20190049 for expression data; Belongs to the citrate synthase family. | 0.469 |
AAO55804.1 | AAO55800.1 | PSPTO_2290 | PSPTO_2286 | Conserved hypothetical protein. | Transcriptional regulator, GntR family; See PMID:20190049 for expression data. | 0.519 |
AAO55804.1 | acnB | PSPTO_2290 | PSPTO_3752 | Conserved hypothetical protein. | Aconitate hydratase 2; Identified by match to TIGR protein family HMM TIGR01342; see PMID:20190049 for expression data; identified by match to TIGR protein family HMM TIGR01342; Belongs to the aconitase/IPM isomerase family. | 0.914 |
AAO55804.1 | prpB | PSPTO_2290 | PSPTO_2287 | Conserved hypothetical protein. | Methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family. | 0.841 |
AAO55804.1 | prpC | PSPTO_2290 | PSPTO_2288 | Conserved hypothetical protein. | 2-methylcitrate synthase; See PMID:20190049 for expression data; Belongs to the citrate synthase family. | 0.879 |
acnB | AAO55804.1 | PSPTO_3752 | PSPTO_2290 | Aconitate hydratase 2; Identified by match to TIGR protein family HMM TIGR01342; see PMID:20190049 for expression data; identified by match to TIGR protein family HMM TIGR01342; Belongs to the aconitase/IPM isomerase family. | Conserved hypothetical protein. | 0.914 |
acnB | prpB | PSPTO_3752 | PSPTO_2287 | Aconitate hydratase 2; Identified by match to TIGR protein family HMM TIGR01342; see PMID:20190049 for expression data; identified by match to TIGR protein family HMM TIGR01342; Belongs to the aconitase/IPM isomerase family. | Methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family. | 0.916 |
acnB | prpC | PSPTO_3752 | PSPTO_2288 | Aconitate hydratase 2; Identified by match to TIGR protein family HMM TIGR01342; see PMID:20190049 for expression data; identified by match to TIGR protein family HMM TIGR01342; Belongs to the aconitase/IPM isomerase family. | 2-methylcitrate synthase; See PMID:20190049 for expression data; Belongs to the citrate synthase family. | 0.789 |
acnB | sucC | PSPTO_3752 | PSPTO_2202 | Aconitate hydratase 2; Identified by match to TIGR protein family HMM TIGR01342; see PMID:20190049 for expression data; identified by match to TIGR protein family HMM TIGR01342; Belongs to the aconitase/IPM isomerase family. | succinyl-CoA synthase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.811 |
acnB | sucD | PSPTO_3752 | PSPTO_2203 | Aconitate hydratase 2; Identified by match to TIGR protein family HMM TIGR01342; see PMID:20190049 for expression data; identified by match to TIGR protein family HMM TIGR01342; Belongs to the aconitase/IPM isomerase family. | succinyl-CoA synthase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.510 |
acs | AAO54286.1 | PSPTO_1825 | PSPTO_0744 | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Thiolase family protein; Belongs to the thiolase-like superfamily. Thiolase family. | 0.934 |
acs | glcB-1 | PSPTO_1825 | PSPTO_0480 | acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. | 0.947 |