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aroE-2 aroE-2 aroK aroK AAO56187.1 AAO56187.1 aroE aroE aroQ aroQ gcd-1 gcd-1 pchA pchA AAO55858.1 AAO55858.1 aroA aroA AAO55268.1 AAO55268.1 guaA guaA
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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Score
aroE-2Shikimate 5-dehydrogenase, putative; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (284 aa)    
Predicted Functional Partners:
aroK
Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family.
 
 0.959
AAO56187.1
Shikimate 5-dehydrogenase, putative; See PMID:20190049 for expression data; identified by match to TIGR protein family HMM TIGR01809.
  
  
 
0.925
aroE
Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
  
  
 
0.924
aroQ
3-dehydroquinate dehydratase, type II; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family.
  
 
 0.923
gcd-1
Glucose dehydrogenase; Similar to SP:Q9XD78, and SP:P15877; identified by sequence similarity; putative.
     
  0.900
pchA
Isochorismate synthase; Involved in the biosynthesis of salicylate (based on the functions of neighboring loci) which is incorporated into the natural product yersiniabactin; see PMID:20190049 for expression data; similar to SP:P23973, and SP:Q51508; identified by sequence similarity; putative.
  
  
 0.854
AAO55858.1
4-hydroxyphenylpyruvate dioxygenase, putative; See PMID:20190049 for expression data; similar to GP:15141381; identified by sequence similarity; putative.
 
  
 0.815
aroA
3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
  
 0.792
AAO55268.1
Prephenate dehydrogenase/3-phosphoshikimate 1-carboxyvinyltransferase family protein; See PMID:20190049 for expression data.
 
  
 0.760
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
 
  
 0.741
Your Current Organism:
Pseudomonas syringae tomato
NCBI taxonomy Id: 223283
Other names: P. syringae pv. tomato str. DC3000, Pseudomonas syringae DC3000, Pseudomonas syringae pv. tomato DC3000, Pseudomonas syringae pv. tomato str. ATCC BAA-871, Pseudomonas syringae pv. tomato str. DC3000
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