node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
guaA | ileS | PSPTO_1450 | PSPTO_0806 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. | 0.670 |
guaA | leuS | PSPTO_1450 | PSPTO_4812 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | leucyl-tRNA synthetase; See PMID:20190049 for expression data; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.543 |
guaA | pheS | PSPTO_1450 | PSPTO_2382 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | phenylalanyl-tRNA synthetase, alpha subunit; See PMID:20190049 for expression data; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. | 0.627 |
guaA | pheT | PSPTO_1450 | PSPTO_2383 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | phenylalanyl-tRNA synthetase, beta subunit; See PMID:20190049 for expression data; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.915 |
guaA | purL | PSPTO_1450 | PSPTO_1459 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.980 |
guaA | pyrD | PSPTO_1450 | PSPTO_2309 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | 0.707 |
guaA | rpoB | PSPTO_1450 | PSPTO_0619 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.923 |
guaA | rpsB | PSPTO_1450 | PSPTO_1534 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | Ribosomal protein S2; See PMID:20190049 for expression data; Belongs to the universal ribosomal protein uS2 family. | 0.719 |
guaA | thrS | PSPTO_1450 | PSPTO_2378 | GMP synthase; Catalyzes the synthesis of GMP from XMP. | threonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr). | 0.691 |
ileS | guaA | PSPTO_0806 | PSPTO_1450 | isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.670 |
ileS | leuS | PSPTO_0806 | PSPTO_4812 | isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. | leucyl-tRNA synthetase; See PMID:20190049 for expression data; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.915 |
ileS | pheS | PSPTO_0806 | PSPTO_2382 | isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. | phenylalanyl-tRNA synthetase, alpha subunit; See PMID:20190049 for expression data; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. | 0.605 |
ileS | pheT | PSPTO_0806 | PSPTO_2383 | isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. | phenylalanyl-tRNA synthetase, beta subunit; See PMID:20190049 for expression data; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.971 |
ileS | purL | PSPTO_0806 | PSPTO_1459 | isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.696 |
ileS | rplO | PSPTO_0806 | PSPTO_0645 | isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. | Ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. | 0.606 |
ileS | rpoB | PSPTO_0806 | PSPTO_0619 | isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.733 |
ileS | rpsB | PSPTO_0806 | PSPTO_1534 | isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. | Ribosomal protein S2; See PMID:20190049 for expression data; Belongs to the universal ribosomal protein uS2 family. | 0.402 |
ileS | thrS | PSPTO_0806 | PSPTO_2378 | isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. | threonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr). | 0.637 |
leuS | guaA | PSPTO_4812 | PSPTO_1450 | leucyl-tRNA synthetase; See PMID:20190049 for expression data; Belongs to the class-I aminoacyl-tRNA synthetase family. | GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.543 |
leuS | ileS | PSPTO_4812 | PSPTO_0806 | leucyl-tRNA synthetase; See PMID:20190049 for expression data; Belongs to the class-I aminoacyl-tRNA synthetase family. | isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. | 0.915 |