STRINGSTRING
poxB poxB hom hom ilvN ilvN sfcA sfcA pyk pyk tdcD tdcD leuD leuD AAO54964.1 AAO54964.1 leuC leuC ppsA ppsA acs acs
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
poxBPyruvate dehydrogenase; Similar to SP:P07003, GB:J03600, GB:J03571, SP:P09917, PID:187167, PID:187169, PID:187193, and PID:388525; identified by sequence similarity; putative; Belongs to the TPP enzyme family. (572 aa)    
Predicted Functional Partners:
hom
Homoserine dehydrogenase; See PMID:20190049 for expression data.
  
 
 0.981
ilvN
Acetolactate synthase, small subunit; Similar to SP:P00894; identified by sequence similarity; putative; see PMID:20190049 for expression data; similar to SP:P00894, identified by sequence similarity, putative.
 
 0.976
sfcA
Malate dehydrogenase; Similar to SP:P26616; identified by sequence similarity; putative; see PMID:20190049 for expression data; similar to SP:P26616, identified by sequence similarity, putative; Belongs to the malic enzymes family.
  
 
 0.924
pyk
Pyruvate kinase; Identified by match to PFAM protein family HMM PF02887; Belongs to the pyruvate kinase family.
  
 0.924
tdcD
Propionate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
    
 0.921
leuD
3-isopropylmalate dehydratase, small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily.
 
 
 0.920
AAO54964.1
Carboxyphosphonoenolpyruvate phosphonomutase; Catalyzes the decarboxylation of oxaloacetate into pyruvate. Seems to play a role in maintaining cellular concentrations of bicarbonate and pyruvate; Belongs to the isocitrate lyase/PEP mutase superfamily. Oxaloacetate decarboxylase family.
  
 
 0.917
leuC
3-isopropylmalate dehydratase, large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
 
 
 0.914
ppsA
Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.
    
 0.913
acs
acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
   
 
 0.909
Your Current Organism:
Pseudomonas syringae tomato
NCBI taxonomy Id: 223283
Other names: P. syringae pv. tomato str. DC3000, Pseudomonas syringae DC3000, Pseudomonas syringae pv. tomato DC3000, Pseudomonas syringae pv. tomato str. ATCC BAA-871, Pseudomonas syringae pv. tomato str. DC3000
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