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AAO56179.1 AAO56179.1 AAO57967.1 AAO57967.1 cmaA cmaA AAO54714.1 AAO54714.1 nuoCD nuoCD fdhA-2 fdhA-2 AAO55102.1 AAO55102.1 cfa6 cfa6 fdH fdH AAO56468.1 AAO56468.1 ku ku
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
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gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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[Homology]
Score
AAO56179.1Oxidoreductase, short chain dehydrogenase/reductase family; Similar to GP:15162052; identified by sequence similarity; putative. (286 aa)    
Predicted Functional Partners:
AAO57967.1
This gene is aparrently the terminal component of a non-ribosomal peptide synthetase (due to the presence of the terminal thioesterase domain) and is most likely associated with the previous gene which appears to be a initiating component. This gene contains three complete amino acid activation, thiolation and condensation domain modules and appears to be specific for glycine, an unidentified amino acid and serine according to the prediction algorithm at http://raynam.chm.jhu.edu/; nrps/index2.html. Taken together these two genes appear to direct the biosynthesis of a previously undesc [...]
  
 
 0.718
cmaA
Coronamic acid synthetase CmaA; Non-ribosomal peptide synthetase with adenylation and thiolation domains; reacts with the AMP derivative of L-allo-isoleucine to produce an aminoacyl thiolester intermediate during coronamic acid biosynthesis; see PMID: 14679222; see PMID:20190049 for expression data; non-ribosomal peptide synthetase with adenylation and thiolation domains, reacts with the AMP derivative of L-allo-isoleucine to produce an aminoacyl thiolester intermediate during coronamic acid biosynthesis, see PMID: 14679222.
 
 
 0.718
AAO54714.1
Oxidoreductase, short chain dehydrogenase/reductase family; See PMID:20190049 for expression data; identified by match to TIGR protein family HMM TIGR01831; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
0.703
nuoCD
NADH dehydrogenase I, C/D subunit; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the N-terminal section; belongs to the complex I 30 kDa subunit family.
   
 
 0.702
fdhA-2
Glutathione-independent formaldehyde dehydrogenase; Similar to SP:P46154; identified by sequence similarity; putative.
 
  
 0.656
AAO55102.1
Oxidoreductase, short-chain dehydrogenase/reductase family; See PMID:20190049 for expression data; similar to GP:5763896, GB:D12799, PID:1163177, and PID:1262583; identified by sequence similarity; putative; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
     0.627
cfa6
Coronafacic acid polyketide synthase I; This gene is the first of two multimodular polyketide synthetases involved in the biosynthesis of coronafacic acid. This synthetase is proposed to receive CPC (2-carboxy-2-cyclopentenone) from an acyl carrier protein (cfa1), it then adds a buyrate group and then completely reduces the ketone of the (former) carboxylate group. The resulting product is then passed to the second polyketide synthetase (cfa7); similar to GP:13346874; identified by sequence similarity; putative; see PMID:20190049 for expression data; This gene is the first of two multi [...]
  
 
 0.612
fdH
Glutathione-dependent formaldehyde dehydrogenase; Similar to SP:P47734; identified by sequence similarity; putative.
 
  
 0.592
AAO56468.1
DNA topoisomerase, type I, putative; Identified by match to PFAM protein family HMM PF01028.
  
 
   0.589
ku
KU domain protein; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family.
 
    0.472
Your Current Organism:
Pseudomonas syringae tomato
NCBI taxonomy Id: 223283
Other names: P. syringae pv. tomato str. DC3000, Pseudomonas syringae DC3000, Pseudomonas syringae pv. tomato DC3000, Pseudomonas syringae pv. tomato str. ATCC BAA-871, Pseudomonas syringae pv. tomato str. DC3000
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