node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AAO56293.1 | AAO56294.1 | PSPTO_2793 | PSPTO_2794 | Conserved hypothetical protein. | Conserved hypothetical protein; Identified by match to PFAM protein family HMM PF00817. | 0.995 |
AAO56293.1 | dnaE2 | PSPTO_2793 | PSPTO_2795 | Conserved hypothetical protein. | DNA polymerase III, alpha subunit, putative; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase. | 0.968 |
AAO56293.1 | lexA-1 | PSPTO_2793 | PSPTO_2792 | Conserved hypothetical protein. | LexA repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | 0.865 |
AAO56294.1 | AAO56293.1 | PSPTO_2794 | PSPTO_2793 | Conserved hypothetical protein; Identified by match to PFAM protein family HMM PF00817. | Conserved hypothetical protein. | 0.995 |
AAO56294.1 | dnaE2 | PSPTO_2794 | PSPTO_2795 | Conserved hypothetical protein; Identified by match to PFAM protein family HMM PF00817. | DNA polymerase III, alpha subunit, putative; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase. | 0.969 |
AAO56294.1 | dnaN | PSPTO_2794 | PSPTO_0002 | Conserved hypothetical protein; Identified by match to PFAM protein family HMM PF00817. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.823 |
AAO56294.1 | holB | PSPTO_2794 | PSPTO_3826 | Conserved hypothetical protein; Identified by match to PFAM protein family HMM PF00817. | DNA polymerase III, delta prime subunit; See PMID:20190049 for expression data; similar to SP:P28631, GB:Z32564, GB:U08470, GB:U08471, GB:Z32633, SP:P14207, SP:P41439, PID:473236, PID:474061, PID:478885, and PID:478887; identified by sequence similarity; putative. | 0.477 |
AAO56294.1 | lexA-1 | PSPTO_2794 | PSPTO_2792 | Conserved hypothetical protein; Identified by match to PFAM protein family HMM PF00817. | LexA repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | 0.886 |
dnaE2 | AAO56293.1 | PSPTO_2795 | PSPTO_2793 | DNA polymerase III, alpha subunit, putative; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase. | Conserved hypothetical protein. | 0.968 |
dnaE2 | AAO56294.1 | PSPTO_2795 | PSPTO_2794 | DNA polymerase III, alpha subunit, putative; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase. | Conserved hypothetical protein; Identified by match to PFAM protein family HMM PF00817. | 0.969 |
dnaE2 | dnaN | PSPTO_2795 | PSPTO_0002 | DNA polymerase III, alpha subunit, putative; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.795 |
dnaE2 | dnaQ | PSPTO_2795 | PSPTO_3711 | DNA polymerase III, alpha subunit, putative; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase. | DNA polymerase III, epsilon subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease. | 0.743 |
dnaE2 | dnaZX | PSPTO_2795 | PSPTO_3646 | DNA polymerase III, alpha subunit, putative; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase. | DNA polymerase III, subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.791 |
dnaE2 | holA | PSPTO_2795 | PSPTO_4814 | DNA polymerase III, alpha subunit, putative; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase. | DNA polymerase III, delta subunit; See PMID:20190049 for expression data. | 0.762 |
dnaE2 | holB | PSPTO_2795 | PSPTO_3826 | DNA polymerase III, alpha subunit, putative; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase. | DNA polymerase III, delta prime subunit; See PMID:20190049 for expression data; similar to SP:P28631, GB:Z32564, GB:U08470, GB:U08471, GB:Z32633, SP:P14207, SP:P41439, PID:473236, PID:474061, PID:478885, and PID:478887; identified by sequence similarity; putative. | 0.743 |
dnaE2 | holC | PSPTO_2795 | PSPTO_1270 | DNA polymerase III, alpha subunit, putative; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase. | DNA polymerase III, chi subunit; See PMID:20190049 for expression data. | 0.727 |
dnaE2 | lexA-1 | PSPTO_2795 | PSPTO_2792 | DNA polymerase III, alpha subunit, putative; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase. | LexA repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | 0.928 |
dnaE2 | ssB | PSPTO_2795 | PSPTO_0656 | DNA polymerase III, alpha subunit, putative; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase. | Single-stranded DNA-binding protein; Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism. | 0.733 |
dnaN | AAO56294.1 | PSPTO_0002 | PSPTO_2794 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Conserved hypothetical protein; Identified by match to PFAM protein family HMM PF00817. | 0.823 |
dnaN | dnaE2 | PSPTO_0002 | PSPTO_2795 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA polymerase III, alpha subunit, putative; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase. | 0.795 |