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pncA pncA pncB pncB cobB2 cobB2 cobB4 cobB4 AAO55884.1 AAO55884.1 nadE nadE AAO56774.1 AAO56774.1 AAO56772.1 AAO56772.1 AAO57967.1 AAO57967.1 cmaA cmaA trmJ trmJ
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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pncAPyrazinamidase/nicotinamidase; See PMID:20190049 for expression data; similar to SP:P21369; identified by sequence similarity; putative. (216 aa)    
Predicted Functional Partners:
pncB
Nicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family.
 
 
 0.973
cobB2
Transcriptional regulator, Sir2 family; NAD-dependent protein deacetylase which modulates the activities of several proteins which are inactive in their acetylated form; Belongs to the sirtuin family. Class III subfamily.
    
 0.907
cobB4
Transcriptional regulator, Sir2 family; NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form; Belongs to the sirtuin family. Class III subfamily.
    
 0.907
AAO55884.1
Inosine/uridine-preferring nucleoside hydrolase; See PMID:20190049 for expression data; Belongs to the IUNH family.
     
 0.901
nadE
NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.
  
  
 0.593
AAO56774.1
Transporter, putative; See PMID:20190049 for expression data; similar to GB:X04143, SP:P02818, and PID:29450; identified by sequence similarity; putative.
  
    0.502
AAO56772.1
TonB-dependent siderophore receptor, putative; See PMID:20190049 for expression data; similar to GP:2981048, and SP:P00089; identified by sequence similarity; putative.
       0.496
AAO57967.1
This gene is aparrently the terminal component of a non-ribosomal peptide synthetase (due to the presence of the terminal thioesterase domain) and is most likely associated with the previous gene which appears to be a initiating component. This gene contains three complete amino acid activation, thiolation and condensation domain modules and appears to be specific for glycine, an unidentified amino acid and serine according to the prediction algorithm at http://raynam.chm.jhu.edu/; nrps/index2.html. Taken together these two genes appear to direct the biosynthesis of a previously undesc [...]
  
 
 0.466
cmaA
Coronamic acid synthetase CmaA; Non-ribosomal peptide synthetase with adenylation and thiolation domains; reacts with the AMP derivative of L-allo-isoleucine to produce an aminoacyl thiolester intermediate during coronamic acid biosynthesis; see PMID: 14679222; see PMID:20190049 for expression data; non-ribosomal peptide synthetase with adenylation and thiolation domains, reacts with the AMP derivative of L-allo-isoleucine to produce an aminoacyl thiolester intermediate during coronamic acid biosynthesis, see PMID: 14679222.
  
 
 0.466
trmJ
RNA methyltransferase, TrmH family, group 1; Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA.
 
      0.434
Your Current Organism:
Pseudomonas syringae tomato
NCBI taxonomy Id: 223283
Other names: P. syringae pv. tomato str. DC3000, Pseudomonas syringae DC3000, Pseudomonas syringae pv. tomato DC3000, Pseudomonas syringae pv. tomato str. ATCC BAA-871, Pseudomonas syringae pv. tomato str. DC3000
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