node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AAO55884.1 | cobB2 | PSPTO_2373 | PSPTO_1704 | Inosine/uridine-preferring nucleoside hydrolase; See PMID:20190049 for expression data; Belongs to the IUNH family. | Transcriptional regulator, Sir2 family; NAD-dependent protein deacetylase which modulates the activities of several proteins which are inactive in their acetylated form; Belongs to the sirtuin family. Class III subfamily. | 0.901 |
AAO55884.1 | cobB4 | PSPTO_2373 | PSPTO_4675 | Inosine/uridine-preferring nucleoside hydrolase; See PMID:20190049 for expression data; Belongs to the IUNH family. | Transcriptional regulator, Sir2 family; NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form; Belongs to the sirtuin family. Class III subfamily. | 0.901 |
AAO55884.1 | pncA | PSPTO_2373 | PSPTO_3295 | Inosine/uridine-preferring nucleoside hydrolase; See PMID:20190049 for expression data; Belongs to the IUNH family. | Pyrazinamidase/nicotinamidase; See PMID:20190049 for expression data; similar to SP:P21369; identified by sequence similarity; putative. | 0.901 |
AAO56772.1 | AAO57967.1 | PSPTO_3294 | PSPTO_4519 | TonB-dependent siderophore receptor, putative; See PMID:20190049 for expression data; similar to GP:2981048, and SP:P00089; identified by sequence similarity; putative. | This gene is aparrently the terminal component of a non-ribosomal peptide synthetase (due to the presence of the terminal thioesterase domain) and is most likely associated with the previous gene which appears to be a initiating component. This gene contains three complete amino acid activation, thiolation and condensation domain modules and appears to be specific for glycine, an unidentified amino acid and serine according to the prediction algorithm at http://raynam.chm.jhu.edu/; nrps/index2.html. Taken together these two genes appear to direct the biosynthesis of a previously undesc [...] | 0.621 |
AAO56772.1 | cmaA | PSPTO_3294 | PSPTO_4709 | TonB-dependent siderophore receptor, putative; See PMID:20190049 for expression data; similar to GP:2981048, and SP:P00089; identified by sequence similarity; putative. | Coronamic acid synthetase CmaA; Non-ribosomal peptide synthetase with adenylation and thiolation domains; reacts with the AMP derivative of L-allo-isoleucine to produce an aminoacyl thiolester intermediate during coronamic acid biosynthesis; see PMID: 14679222; see PMID:20190049 for expression data; non-ribosomal peptide synthetase with adenylation and thiolation domains, reacts with the AMP derivative of L-allo-isoleucine to produce an aminoacyl thiolester intermediate during coronamic acid biosynthesis, see PMID: 14679222. | 0.621 |
AAO56772.1 | pncA | PSPTO_3294 | PSPTO_3295 | TonB-dependent siderophore receptor, putative; See PMID:20190049 for expression data; similar to GP:2981048, and SP:P00089; identified by sequence similarity; putative. | Pyrazinamidase/nicotinamidase; See PMID:20190049 for expression data; similar to SP:P21369; identified by sequence similarity; putative. | 0.496 |
AAO56774.1 | pncA | PSPTO_3296 | PSPTO_3295 | Transporter, putative; See PMID:20190049 for expression data; similar to GB:X04143, SP:P02818, and PID:29450; identified by sequence similarity; putative. | Pyrazinamidase/nicotinamidase; See PMID:20190049 for expression data; similar to SP:P21369; identified by sequence similarity; putative. | 0.502 |
AAO57967.1 | AAO56772.1 | PSPTO_4519 | PSPTO_3294 | This gene is aparrently the terminal component of a non-ribosomal peptide synthetase (due to the presence of the terminal thioesterase domain) and is most likely associated with the previous gene which appears to be a initiating component. This gene contains three complete amino acid activation, thiolation and condensation domain modules and appears to be specific for glycine, an unidentified amino acid and serine according to the prediction algorithm at http://raynam.chm.jhu.edu/; nrps/index2.html. Taken together these two genes appear to direct the biosynthesis of a previously undesc [...] | TonB-dependent siderophore receptor, putative; See PMID:20190049 for expression data; similar to GP:2981048, and SP:P00089; identified by sequence similarity; putative. | 0.621 |
AAO57967.1 | cmaA | PSPTO_4519 | PSPTO_4709 | This gene is aparrently the terminal component of a non-ribosomal peptide synthetase (due to the presence of the terminal thioesterase domain) and is most likely associated with the previous gene which appears to be a initiating component. This gene contains three complete amino acid activation, thiolation and condensation domain modules and appears to be specific for glycine, an unidentified amino acid and serine according to the prediction algorithm at http://raynam.chm.jhu.edu/; nrps/index2.html. Taken together these two genes appear to direct the biosynthesis of a previously undesc [...] | Coronamic acid synthetase CmaA; Non-ribosomal peptide synthetase with adenylation and thiolation domains; reacts with the AMP derivative of L-allo-isoleucine to produce an aminoacyl thiolester intermediate during coronamic acid biosynthesis; see PMID: 14679222; see PMID:20190049 for expression data; non-ribosomal peptide synthetase with adenylation and thiolation domains, reacts with the AMP derivative of L-allo-isoleucine to produce an aminoacyl thiolester intermediate during coronamic acid biosynthesis, see PMID: 14679222. | 0.999 |
AAO57967.1 | nadE | PSPTO_4519 | PSPTO_4922 | This gene is aparrently the terminal component of a non-ribosomal peptide synthetase (due to the presence of the terminal thioesterase domain) and is most likely associated with the previous gene which appears to be a initiating component. This gene contains three complete amino acid activation, thiolation and condensation domain modules and appears to be specific for glycine, an unidentified amino acid and serine according to the prediction algorithm at http://raynam.chm.jhu.edu/; nrps/index2.html. Taken together these two genes appear to direct the biosynthesis of a previously undesc [...] | NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | 0.545 |
AAO57967.1 | pncA | PSPTO_4519 | PSPTO_3295 | This gene is aparrently the terminal component of a non-ribosomal peptide synthetase (due to the presence of the terminal thioesterase domain) and is most likely associated with the previous gene which appears to be a initiating component. This gene contains three complete amino acid activation, thiolation and condensation domain modules and appears to be specific for glycine, an unidentified amino acid and serine according to the prediction algorithm at http://raynam.chm.jhu.edu/; nrps/index2.html. Taken together these two genes appear to direct the biosynthesis of a previously undesc [...] | Pyrazinamidase/nicotinamidase; See PMID:20190049 for expression data; similar to SP:P21369; identified by sequence similarity; putative. | 0.466 |
cmaA | AAO56772.1 | PSPTO_4709 | PSPTO_3294 | Coronamic acid synthetase CmaA; Non-ribosomal peptide synthetase with adenylation and thiolation domains; reacts with the AMP derivative of L-allo-isoleucine to produce an aminoacyl thiolester intermediate during coronamic acid biosynthesis; see PMID: 14679222; see PMID:20190049 for expression data; non-ribosomal peptide synthetase with adenylation and thiolation domains, reacts with the AMP derivative of L-allo-isoleucine to produce an aminoacyl thiolester intermediate during coronamic acid biosynthesis, see PMID: 14679222. | TonB-dependent siderophore receptor, putative; See PMID:20190049 for expression data; similar to GP:2981048, and SP:P00089; identified by sequence similarity; putative. | 0.621 |
cmaA | AAO57967.1 | PSPTO_4709 | PSPTO_4519 | Coronamic acid synthetase CmaA; Non-ribosomal peptide synthetase with adenylation and thiolation domains; reacts with the AMP derivative of L-allo-isoleucine to produce an aminoacyl thiolester intermediate during coronamic acid biosynthesis; see PMID: 14679222; see PMID:20190049 for expression data; non-ribosomal peptide synthetase with adenylation and thiolation domains, reacts with the AMP derivative of L-allo-isoleucine to produce an aminoacyl thiolester intermediate during coronamic acid biosynthesis, see PMID: 14679222. | This gene is aparrently the terminal component of a non-ribosomal peptide synthetase (due to the presence of the terminal thioesterase domain) and is most likely associated with the previous gene which appears to be a initiating component. This gene contains three complete amino acid activation, thiolation and condensation domain modules and appears to be specific for glycine, an unidentified amino acid and serine according to the prediction algorithm at http://raynam.chm.jhu.edu/; nrps/index2.html. Taken together these two genes appear to direct the biosynthesis of a previously undesc [...] | 0.999 |
cmaA | nadE | PSPTO_4709 | PSPTO_4922 | Coronamic acid synthetase CmaA; Non-ribosomal peptide synthetase with adenylation and thiolation domains; reacts with the AMP derivative of L-allo-isoleucine to produce an aminoacyl thiolester intermediate during coronamic acid biosynthesis; see PMID: 14679222; see PMID:20190049 for expression data; non-ribosomal peptide synthetase with adenylation and thiolation domains, reacts with the AMP derivative of L-allo-isoleucine to produce an aminoacyl thiolester intermediate during coronamic acid biosynthesis, see PMID: 14679222. | NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | 0.545 |
cmaA | pncA | PSPTO_4709 | PSPTO_3295 | Coronamic acid synthetase CmaA; Non-ribosomal peptide synthetase with adenylation and thiolation domains; reacts with the AMP derivative of L-allo-isoleucine to produce an aminoacyl thiolester intermediate during coronamic acid biosynthesis; see PMID: 14679222; see PMID:20190049 for expression data; non-ribosomal peptide synthetase with adenylation and thiolation domains, reacts with the AMP derivative of L-allo-isoleucine to produce an aminoacyl thiolester intermediate during coronamic acid biosynthesis, see PMID: 14679222. | Pyrazinamidase/nicotinamidase; See PMID:20190049 for expression data; similar to SP:P21369; identified by sequence similarity; putative. | 0.466 |
cobB2 | AAO55884.1 | PSPTO_1704 | PSPTO_2373 | Transcriptional regulator, Sir2 family; NAD-dependent protein deacetylase which modulates the activities of several proteins which are inactive in their acetylated form; Belongs to the sirtuin family. Class III subfamily. | Inosine/uridine-preferring nucleoside hydrolase; See PMID:20190049 for expression data; Belongs to the IUNH family. | 0.901 |
cobB2 | cobB4 | PSPTO_1704 | PSPTO_4675 | Transcriptional regulator, Sir2 family; NAD-dependent protein deacetylase which modulates the activities of several proteins which are inactive in their acetylated form; Belongs to the sirtuin family. Class III subfamily. | Transcriptional regulator, Sir2 family; NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form; Belongs to the sirtuin family. Class III subfamily. | 0.925 |
cobB2 | nadE | PSPTO_1704 | PSPTO_4922 | Transcriptional regulator, Sir2 family; NAD-dependent protein deacetylase which modulates the activities of several proteins which are inactive in their acetylated form; Belongs to the sirtuin family. Class III subfamily. | NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | 0.911 |
cobB2 | pncA | PSPTO_1704 | PSPTO_3295 | Transcriptional regulator, Sir2 family; NAD-dependent protein deacetylase which modulates the activities of several proteins which are inactive in their acetylated form; Belongs to the sirtuin family. Class III subfamily. | Pyrazinamidase/nicotinamidase; See PMID:20190049 for expression data; similar to SP:P21369; identified by sequence similarity; putative. | 0.907 |
cobB4 | AAO55884.1 | PSPTO_4675 | PSPTO_2373 | Transcriptional regulator, Sir2 family; NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form; Belongs to the sirtuin family. Class III subfamily. | Inosine/uridine-preferring nucleoside hydrolase; See PMID:20190049 for expression data; Belongs to the IUNH family. | 0.901 |