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acnB acnB gltA gltA AAO56834.1 AAO56834.1 acnA acnA prpB prpB aceA aceA AAO55804.1 AAO55804.1 sucC sucC AAO57790.1 AAO57790.1 sucA sucA prpC prpC
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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acnBAconitate hydratase 2; Identified by match to TIGR protein family HMM TIGR01342; see PMID:20190049 for expression data; identified by match to TIGR protein family HMM TIGR01342; Belongs to the aconitase/IPM isomerase family. (866 aa)    
Predicted Functional Partners:
gltA
Citrate synthase I; Similar to PIR:A33596; identified by sequence similarity; putative; Belongs to the citrate synthase family.
  
 
 0.983
AAO56834.1
Isocitrate dehydrogenase, NADP-dependent; See PMID:20190049 for expression data; Belongs to the monomeric-type IDH family.
 
 
 0.948
acnA
Aconitate hydratase 1; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.
    
 0.926
prpB
Methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
     
 0.916
aceA
Isocitrate lyase.
     
 0.916
AAO55804.1
Conserved hypothetical protein.
    
 0.914
sucC
succinyl-CoA synthase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
  
 0.811
AAO57790.1
Fumarate hydratase, class I, putative; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
  
  
 0.806
sucA
2-oxoglutarate dehydrogenase, E1 component; Identified by match to PFAM protein family HMM PF02779; see PMID:20190049 for expression data; identified by match to PFAM protein family HMM PF02779.
   
  
 0.792
prpC
2-methylcitrate synthase; See PMID:20190049 for expression data; Belongs to the citrate synthase family.
  
  
 0.789
Your Current Organism:
Pseudomonas syringae tomato
NCBI taxonomy Id: 223283
Other names: P. syringae pv. tomato str. DC3000, Pseudomonas syringae DC3000, Pseudomonas syringae pv. tomato DC3000, Pseudomonas syringae pv. tomato str. ATCC BAA-871, Pseudomonas syringae pv. tomato str. DC3000
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