node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AAO55943.1 | AAO57386.1 | PSPTO_2434 | PSPTO_3920 | D-isomer specific 2-hydroxyacid dehydrogenase family protein; Identified by match to PFAM protein family HMM PF02826; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | D-isomer specific 2-hydroxyacid dehydrogenase family protein; See PMID:20190049 for expression data. | 0.730 |
AAO55943.1 | cfa6 | PSPTO_2434 | PSPTO_4686 | D-isomer specific 2-hydroxyacid dehydrogenase family protein; Identified by match to PFAM protein family HMM PF02826; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Coronafacic acid polyketide synthase I; This gene is the first of two multimodular polyketide synthetases involved in the biosynthesis of coronafacic acid. This synthetase is proposed to receive CPC (2-carboxy-2-cyclopentenone) from an acyl carrier protein (cfa1), it then adds a buyrate group and then completely reduces the ketone of the (former) carboxylate group. The resulting product is then passed to the second polyketide synthetase (cfa7); similar to GP:13346874; identified by sequence similarity; putative; see PMID:20190049 for expression data; This gene is the first of two multi [...] | 0.569 |
AAO57386.1 | AAO55943.1 | PSPTO_3920 | PSPTO_2434 | D-isomer specific 2-hydroxyacid dehydrogenase family protein; See PMID:20190049 for expression data. | D-isomer specific 2-hydroxyacid dehydrogenase family protein; Identified by match to PFAM protein family HMM PF02826; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.730 |
AAO57386.1 | AAO57387.1 | PSPTO_3920 | PSPTO_3921 | D-isomer specific 2-hydroxyacid dehydrogenase family protein; See PMID:20190049 for expression data. | Conserved protein of unknown function; See PMID:20190049 for expression data; identified by Glimmer. | 0.606 |
AAO57386.1 | AAO57967.1 | PSPTO_3920 | PSPTO_4519 | D-isomer specific 2-hydroxyacid dehydrogenase family protein; See PMID:20190049 for expression data. | This gene is aparrently the terminal component of a non-ribosomal peptide synthetase (due to the presence of the terminal thioesterase domain) and is most likely associated with the previous gene which appears to be a initiating component. This gene contains three complete amino acid activation, thiolation and condensation domain modules and appears to be specific for glycine, an unidentified amino acid and serine according to the prediction algorithm at http://raynam.chm.jhu.edu/; nrps/index2.html. Taken together these two genes appear to direct the biosynthesis of a previously undesc [...] | 0.474 |
AAO57386.1 | birA | PSPTO_3920 | PSPTO_0610 | D-isomer specific 2-hydroxyacid dehydrogenase family protein; See PMID:20190049 for expression data. | birA bifunctional protein; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 0.411 |
AAO57386.1 | cfa6 | PSPTO_3920 | PSPTO_4686 | D-isomer specific 2-hydroxyacid dehydrogenase family protein; See PMID:20190049 for expression data. | Coronafacic acid polyketide synthase I; This gene is the first of two multimodular polyketide synthetases involved in the biosynthesis of coronafacic acid. This synthetase is proposed to receive CPC (2-carboxy-2-cyclopentenone) from an acyl carrier protein (cfa1), it then adds a buyrate group and then completely reduces the ketone of the (former) carboxylate group. The resulting product is then passed to the second polyketide synthetase (cfa7); similar to GP:13346874; identified by sequence similarity; putative; see PMID:20190049 for expression data; This gene is the first of two multi [...] | 0.479 |
AAO57386.1 | cmaA | PSPTO_3920 | PSPTO_4709 | D-isomer specific 2-hydroxyacid dehydrogenase family protein; See PMID:20190049 for expression data. | Coronamic acid synthetase CmaA; Non-ribosomal peptide synthetase with adenylation and thiolation domains; reacts with the AMP derivative of L-allo-isoleucine to produce an aminoacyl thiolester intermediate during coronamic acid biosynthesis; see PMID: 14679222; see PMID:20190049 for expression data; non-ribosomal peptide synthetase with adenylation and thiolation domains, reacts with the AMP derivative of L-allo-isoleucine to produce an aminoacyl thiolester intermediate during coronamic acid biosynthesis, see PMID: 14679222. | 0.474 |
AAO57386.1 | hom | PSPTO_3920 | PSPTO_1480 | D-isomer specific 2-hydroxyacid dehydrogenase family protein; See PMID:20190049 for expression data. | Homoserine dehydrogenase; See PMID:20190049 for expression data. | 0.625 |
AAO57386.1 | maf-2 | PSPTO_3920 | PSPTO_4469 | D-isomer specific 2-hydroxyacid dehydrogenase family protein; See PMID:20190049 for expression data. | Maf protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | 0.400 |
AAO57386.1 | rnd | PSPTO_3920 | PSPTO_3922 | D-isomer specific 2-hydroxyacid dehydrogenase family protein; See PMID:20190049 for expression data. | Ribonuclease D; Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides; Belongs to the RNase D family. | 0.606 |
AAO57386.1 | serC | PSPTO_3920 | PSPTO_1746 | D-isomer specific 2-hydroxyacid dehydrogenase family protein; See PMID:20190049 for expression data. | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. | 0.600 |
AAO57387.1 | AAO57386.1 | PSPTO_3921 | PSPTO_3920 | Conserved protein of unknown function; See PMID:20190049 for expression data; identified by Glimmer. | D-isomer specific 2-hydroxyacid dehydrogenase family protein; See PMID:20190049 for expression data. | 0.606 |
AAO57387.1 | rnd | PSPTO_3921 | PSPTO_3922 | Conserved protein of unknown function; See PMID:20190049 for expression data; identified by Glimmer. | Ribonuclease D; Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides; Belongs to the RNase D family. | 0.912 |
AAO57967.1 | AAO57386.1 | PSPTO_4519 | PSPTO_3920 | This gene is aparrently the terminal component of a non-ribosomal peptide synthetase (due to the presence of the terminal thioesterase domain) and is most likely associated with the previous gene which appears to be a initiating component. This gene contains three complete amino acid activation, thiolation and condensation domain modules and appears to be specific for glycine, an unidentified amino acid and serine according to the prediction algorithm at http://raynam.chm.jhu.edu/; nrps/index2.html. Taken together these two genes appear to direct the biosynthesis of a previously undesc [...] | D-isomer specific 2-hydroxyacid dehydrogenase family protein; See PMID:20190049 for expression data. | 0.474 |
AAO57967.1 | birA | PSPTO_4519 | PSPTO_0610 | This gene is aparrently the terminal component of a non-ribosomal peptide synthetase (due to the presence of the terminal thioesterase domain) and is most likely associated with the previous gene which appears to be a initiating component. This gene contains three complete amino acid activation, thiolation and condensation domain modules and appears to be specific for glycine, an unidentified amino acid and serine according to the prediction algorithm at http://raynam.chm.jhu.edu/; nrps/index2.html. Taken together these two genes appear to direct the biosynthesis of a previously undesc [...] | birA bifunctional protein; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 0.587 |
AAO57967.1 | cfa6 | PSPTO_4519 | PSPTO_4686 | This gene is aparrently the terminal component of a non-ribosomal peptide synthetase (due to the presence of the terminal thioesterase domain) and is most likely associated with the previous gene which appears to be a initiating component. This gene contains three complete amino acid activation, thiolation and condensation domain modules and appears to be specific for glycine, an unidentified amino acid and serine according to the prediction algorithm at http://raynam.chm.jhu.edu/; nrps/index2.html. Taken together these two genes appear to direct the biosynthesis of a previously undesc [...] | Coronafacic acid polyketide synthase I; This gene is the first of two multimodular polyketide synthetases involved in the biosynthesis of coronafacic acid. This synthetase is proposed to receive CPC (2-carboxy-2-cyclopentenone) from an acyl carrier protein (cfa1), it then adds a buyrate group and then completely reduces the ketone of the (former) carboxylate group. The resulting product is then passed to the second polyketide synthetase (cfa7); similar to GP:13346874; identified by sequence similarity; putative; see PMID:20190049 for expression data; This gene is the first of two multi [...] | 0.999 |
AAO57967.1 | cmaA | PSPTO_4519 | PSPTO_4709 | This gene is aparrently the terminal component of a non-ribosomal peptide synthetase (due to the presence of the terminal thioesterase domain) and is most likely associated with the previous gene which appears to be a initiating component. This gene contains three complete amino acid activation, thiolation and condensation domain modules and appears to be specific for glycine, an unidentified amino acid and serine according to the prediction algorithm at http://raynam.chm.jhu.edu/; nrps/index2.html. Taken together these two genes appear to direct the biosynthesis of a previously undesc [...] | Coronamic acid synthetase CmaA; Non-ribosomal peptide synthetase with adenylation and thiolation domains; reacts with the AMP derivative of L-allo-isoleucine to produce an aminoacyl thiolester intermediate during coronamic acid biosynthesis; see PMID: 14679222; see PMID:20190049 for expression data; non-ribosomal peptide synthetase with adenylation and thiolation domains, reacts with the AMP derivative of L-allo-isoleucine to produce an aminoacyl thiolester intermediate during coronamic acid biosynthesis, see PMID: 14679222. | 0.999 |
birA | AAO57386.1 | PSPTO_0610 | PSPTO_3920 | birA bifunctional protein; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | D-isomer specific 2-hydroxyacid dehydrogenase family protein; See PMID:20190049 for expression data. | 0.411 |
birA | AAO57967.1 | PSPTO_0610 | PSPTO_4519 | birA bifunctional protein; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | This gene is aparrently the terminal component of a non-ribosomal peptide synthetase (due to the presence of the terminal thioesterase domain) and is most likely associated with the previous gene which appears to be a initiating component. This gene contains three complete amino acid activation, thiolation and condensation domain modules and appears to be specific for glycine, an unidentified amino acid and serine according to the prediction algorithm at http://raynam.chm.jhu.edu/; nrps/index2.html. Taken together these two genes appear to direct the biosynthesis of a previously undesc [...] | 0.587 |