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kefC kefC kefF kefF gor-1 gor-1 AAO55250.1 AAO55250.1 flgG flgG gshA gshA nhaP2 nhaP2 AAO57711.1 AAO57711.1 gshB gshB trkH trkH AAO53910.1 AAO53910.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Score
kefCGlutathione-regulated potassium-efflux system protein; Pore-forming subunit of a potassium efflux system that confers protection against electrophiles. Catalyzes K(+)/H(+) antiport. (607 aa)    
Predicted Functional Partners:
kefF
NAD(P)H dehydrogenase, quinone family; Regulatory subunit of a potassium efflux system that confers protection against electrophiles. Required for full activity of KefC. Shows redox enzymatic activity, but this enzymatic activity is not required for activation of KefC; Belongs to the NAD(P)H dehydrogenase (quinone) family. KefF subfamily.
 
 
 0.997
gor-1
Glutathione reductase; See PMID:20190049 for expression data.
     
 0.840
AAO55250.1
NAD(P)H dehydrogenase, quinone family; See PMID:20190049 for expression data; similar to GP:14523747; identified by sequence similarity; putative.
  
 
 0.694
flgG
Flagellar basal-body rod protein FlgG; See PMID:20190049 for expression data; similar to SP:P75939, GB:M11186, GB:M62611, SP:P01178, PID:189411, PID:386991, and PID:825699; identified by sequence similarity; putative; Belongs to the flagella basal body rod proteins family.
    
   0.614
gshA
Glutamate--cysteine ligase; See PMID:20190049 for expression data; Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily.
      
 0.605
nhaP2
Sodium/hydrogen exchanger family protein; K(+)/H(+) antiporter that extrudes potassium in exchange for external protons and maintains the internal concentration of potassium under toxic levels; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. NhaP2 subfamily.
     
 0.525
AAO57711.1
4-oxalocrotonate tautomerase family protein; See PMID:20190049 for expression data; similar to GB:M31470, SP:P17081, and PID:190881; identified by sequence similarity; putative; Belongs to the 4-oxalocrotonate tautomerase family.
       0.517
gshB
Glutathione synthetase; See PMID:20190049 for expression data.
     
 0.511
trkH
Potassium uptake protein TrkH; Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA; Belongs to the TrkH potassium transport family.
   
 
 0.482
AAO53910.1
Na+/H+ antiporter NhaP; Identified by match to PFAM protein family HMM PF04172.
   
 
 0.474
Your Current Organism:
Pseudomonas syringae tomato
NCBI taxonomy Id: 223283
Other names: P. syringae pv. tomato str. DC3000, Pseudomonas syringae DC3000, Pseudomonas syringae pv. tomato DC3000, Pseudomonas syringae pv. tomato str. ATCC BAA-871, Pseudomonas syringae pv. tomato str. DC3000
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