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ahcY ahcY metE metE metH metH metC-1 metC-1 metZ metZ metC-2 metC-2 AAO56135.1 AAO56135.1 AAO55897.1 AAO55897.1 AAO56905.1 AAO56905.1 cysK cysK metK metK
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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ahcYAdenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. (469 aa)    
Predicted Functional Partners:
metE
5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.
  
 
 0.972
metH
5-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
 
 0.961
metC-1
Cystathionine beta-lyase; See PMID:20190049 for expression data; similar to SP:P06721; identified by sequence similarity; putative.
  
 0.918
metZ
O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide.
  
 0.918
metC-2
Cystathionine beta-lyase; Similar to SP:P06721; identified by sequence similarity; putative.
  
 0.918
AAO56135.1
Rhodanese domain protein/cystathionine beta-lyase; See PMID:20190049 for expression data; identified by match to TIGR protein family HMM TIGR00858.
   
 
 0.908
AAO55897.1
C-5 cytosine-specific DNA methylase family protein; See PMID:20190049 for expression data; identified by match to TIGR protein family HMM TIGR00675; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.
     
 0.906
AAO56905.1
C-5 cytosine-specific DNA methylase family protein; Identified by match to TIGR protein family HMM TIGR00675.
     
 0.906
cysK
Cysteine synthase A; See PMID:20190049 for expression data; Belongs to the cysteine synthase/cystathionine beta- synthase family.
  
 0.839
metK
S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
 
 
 0.834
Your Current Organism:
Pseudomonas syringae tomato
NCBI taxonomy Id: 223283
Other names: P. syringae pv. tomato str. DC3000, Pseudomonas syringae DC3000, Pseudomonas syringae pv. tomato DC3000, Pseudomonas syringae pv. tomato str. ATCC BAA-871, Pseudomonas syringae pv. tomato str. DC3000
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