node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AAO58889.1 | AAO58891.1 | PSPTO_5470 | PSPTO_5472 | Conserved hypothetical protein; Identified by Glimmer2; putative. | DNA-binding protein HU family; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | 0.480 |
AAO58889.1 | rubA | PSPTO_5470 | PSPTO_5474 | Conserved hypothetical protein; Identified by Glimmer2; putative. | Rubredoxin; See PMID:20190049 for expression data. | 0.408 |
AAO58889.1 | rubB | PSPTO_5470 | PSPTO_5473 | Conserved hypothetical protein; Identified by Glimmer2; putative. | Rubredoxin reductase; See PMID:20190049 for expression data; Belongs to the FAD-dependent oxidoreductase family. | 0.618 |
AAO58891.1 | AAO58889.1 | PSPTO_5472 | PSPTO_5470 | DNA-binding protein HU family; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | Conserved hypothetical protein; Identified by Glimmer2; putative. | 0.480 |
AAO58891.1 | dnaA | PSPTO_5472 | PSPTO_0001 | DNA-binding protein HU family; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | 0.438 |
AAO58891.1 | ihfA | PSPTO_5472 | PSPTO_2384 | DNA-binding protein HU family; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | Integration host factor, alpha subunit; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family. | 0.549 |
AAO58891.1 | pheA | PSPTO_5472 | PSPTO_1747 | DNA-binding protein HU family; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | Chorismate mutase/prephenate dehydratase; See PMID:20190049 for expression data. | 0.513 |
AAO58891.1 | polI | PSPTO_5472 | PSPTO_0344 | DNA-binding protein HU family; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.464 |
AAO58891.1 | rpsO | PSPTO_5472 | PSPTO_4487 | DNA-binding protein HU family; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | Ribosomal protein S15; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA. | 0.564 |
AAO58891.1 | rpsT | PSPTO_5472 | PSPTO_0802 | DNA-binding protein HU family; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | Ribosomal protein S20; Binds directly to 16S ribosomal RNA. | 0.458 |
AAO58891.1 | rubA | PSPTO_5472 | PSPTO_5474 | DNA-binding protein HU family; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | Rubredoxin; See PMID:20190049 for expression data. | 0.484 |
AAO58891.1 | rubB | PSPTO_5472 | PSPTO_5473 | DNA-binding protein HU family; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | Rubredoxin reductase; See PMID:20190049 for expression data; Belongs to the FAD-dependent oxidoreductase family. | 0.556 |
AAO58891.1 | topA | PSPTO_5472 | PSPTO_3514 | DNA-binding protein HU family; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.503 |
dnaA | AAO58891.1 | PSPTO_0001 | PSPTO_5472 | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | DNA-binding protein HU family; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | 0.438 |
dnaA | ihfA | PSPTO_0001 | PSPTO_2384 | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | Integration host factor, alpha subunit; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family. | 0.501 |
dnaA | polI | PSPTO_0001 | PSPTO_0344 | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.559 |
dnaA | topA | PSPTO_0001 | PSPTO_3514 | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.511 |
ihfA | AAO58891.1 | PSPTO_2384 | PSPTO_5472 | Integration host factor, alpha subunit; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family. | DNA-binding protein HU family; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. | 0.549 |
ihfA | dnaA | PSPTO_2384 | PSPTO_0001 | Integration host factor, alpha subunit; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family. | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | 0.501 |
ihfA | pheA | PSPTO_2384 | PSPTO_1747 | Integration host factor, alpha subunit; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family. | Chorismate mutase/prephenate dehydratase; See PMID:20190049 for expression data. | 0.513 |