STRINGSTRING
glmU glmU glmM glmM murA murA AAO54723.1 AAO54723.1 glmS glmS wbpM wbpM AAO54097.1 AAO54097.1 prsA prsA lpxA lpxA pta pta murE murE
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Predicted Interactions
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gene co-occurrence
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textmining
co-expression
protein homology
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glmUUDP-N-acetylglucosamine pyrophosphorylase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family. (455 aa)    
Predicted Functional Partners:
glmM
Phosphoglucosamine mutase; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate; Belongs to the phosphohexose mutase family.
 
 
 0.969
murA
UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.
 
 
 0.953
AAO54723.1
UDP-N-acetylglucosamine 2-epimerase; Identified by match to TIGR protein family HMM TIGR00236; Belongs to the UDP-N-acetylglucosamine 2-epimerase family.
 
  
 0.952
glmS
Glucosamine--fructose-6-phosphate aminotransferase, isomerizing; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
  
 0.938
wbpM
Nucleotide sugar epimerase/dehydratase WbpM; See PMID:20190049 for expression data.
    
 0.923
AAO54097.1
Conserved protein of unknown function; See PMID:20190049 for expression data; similar to GP:4545243, and GP:4545243; identified by sequence similarity; putative.
    
 0.919
prsA
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
 
  
 0.909
lpxA
acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
  
 
 0.866
pta
Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
  
 
 0.823
murE
UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily.
 
  
 0.801
Your Current Organism:
Pseudomonas syringae tomato
NCBI taxonomy Id: 223283
Other names: P. syringae pv. tomato str. DC3000, Pseudomonas syringae DC3000, Pseudomonas syringae pv. tomato DC3000, Pseudomonas syringae pv. tomato str. ATCC BAA-871, Pseudomonas syringae pv. tomato str. DC3000
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