STRINGSTRING
AEF22878.1 AEF22878.1 topA topA AEF22542.1 AEF22542.1 AEF23084.1 AEF23084.1 AEF23308.1 AEF23308.1 AEF23302.1 AEF23302.1 AEF22877.1 AEF22877.1 AEF23443.1 AEF23443.1 AEF20996.1 AEF20996.1 AEF22650.1 AEF22650.1 AEF22583.1 AEF22583.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AEF22878.1KEGG: psa:PST_1730 hypothetical protein. (173 aa)    
Predicted Functional Partners:
topA
DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
 
     0.773
AEF22542.1
KEGG: pmy:Pmen_2458 hypothetical protein.
  
     0.745
AEF23084.1
KEGG: pmy:Pmen_2891 Arc domain-containing protein.
  
     0.742
AEF23308.1
KEGG: pfo:Pfl01_1219 hypothetical protein.
  
     0.738
AEF23302.1
Beta-agarase; KEGG: avn:Avin_19460 agarase.
  
     0.707
AEF22877.1
KEGG: pmy:Pmen_1585 hypothetical protein.
 
    0.706
AEF23443.1
KEGG: pmy:Pmen_4438 hypothetical protein.
  
     0.692
AEF20996.1
PFAM: Outer membrane porin, bacterial; KEGG: ppg:PputGB1_4239 outer membrane porin.
  
     0.682
AEF22650.1
KEGG: pmy:Pmen_1916 hypothetical protein.
  
     0.681
AEF22583.1
PFAM: Outer membrane porin, bacterial; KEGG: ppg:PputGB1_4239 outer membrane porin.
  
     0.678
Your Current Organism:
Pseudomonas fulva
NCBI taxonomy Id: 743720
Other names: P. fulva 12-X, Pseudomonas fulva 12-X, Pseudomonas fulva str. 12-X, Pseudomonas fulva strain 12-X
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