STRINGSTRING
AEF20133.1 AEF20133.1 AEF20132.1 AEF20132.1 trpA trpA trpB trpB AEF23490.1 AEF23490.1 AEF24278.1 AEF24278.1 trpE trpE AEF21989.1 AEF21989.1 trpC trpC AEF20134.1 AEF20134.1 AEF24117.1 AEF24117.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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[Homology]
Score
AEF20133.1PFAM: HTH transcriptional regulator, LysR; LysR, substrate-binding; KEGG: psa:PST_2894 transcriptional regulator TrpI; Belongs to the LysR transcriptional regulatory family. (297 aa)    
Predicted Functional Partners:
AEF20132.1
KEGG: pmy:Pmen_0072 hypothetical protein.
       0.805
trpA
Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
     
 0.704
trpB
Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
     
 0.692
AEF23490.1
PFAM: LysR, substrate-binding; HTH transcriptional regulator, LysR; KEGG: psp:PSPPH_1758 LysR family transcriptional regulator; Belongs to the LysR transcriptional regulatory family.
  
     0.646
AEF24278.1
PFAM: LysR, substrate-binding; HTH transcriptional regulator, LysR; KEGG: ebi:EbC_30560 LysR family regulatory protein.
  
     0.636
trpE
Anthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...]
      
 0.604
AEF21989.1
Chorismate mutase; TIGRFAM: Gamma/beta/epsilon proteobacterial P-protein, chorismate mutase domain; PFAM: Prephenate dehydratase; Chorismate mutase, type II; Amino acid-binding ACT; KEGG: pmy:Pmen_1850 prephenate dehydratase; SMART: Chorismate mutase.
      
 0.604
trpC
KEGG: psb:Psyr_4579 indole-3-glycerol-phosphate synthase; PFAM: Indole-3-glycerol phosphate synthase; Belongs to the TrpC family.
      
 0.598
AEF20134.1
KEGG: psa:PST_2893 hypothetical protein.
       0.593
AEF24117.1
PFAM: LysR, substrate-binding; HTH transcriptional regulator, LysR; KEGG: pap:PSPA7_5724 putative transcriptional regulator; Belongs to the LysR transcriptional regulatory family.
  
     0.584
Your Current Organism:
Pseudomonas fulva
NCBI taxonomy Id: 743720
Other names: P. fulva 12-X, Pseudomonas fulva 12-X, Pseudomonas fulva str. 12-X, Pseudomonas fulva strain 12-X
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